| Type | Description |
|---|---|
| Definition | phosphodiesterase 5A |
| Date | Results | Publications |
|---|---|---|
| 2014-05-24 12:00:00 | Phosphodiesterase-5 activity exerts a vasoconstrictor influence on coronary resistance vessels that is mediated, in part, via an increase in endothelial endothelin production. | 24464751 |
| 2014-05-24 11:17:00 | PDE5 inhibition and increase in cGMP produce pulmonary vasodilation that is mediated in part through inhibition of the ET pathway, thereby precluding an additional vasodilator effect of ETA/ETB receptor blockade in the presence of PDE5 inhibition. | 24414253 |
| 2012-04-14 10:48:00 | Endothelial dysfunction enhances the pulmonary and systemic vasodilator effects of phosphodiesterase-5 inhibition in awake swine at rest and during treadmill exercise | 22312057 |
| 2010-01-21 00:00:00 | PDE5 is a key regulator of NO-induced vasodilation in the postnatal pulmonary arteries. | 15295092 |
| Type | IDs |
|---|---|
| Synonymous | PDE5 |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
XP_020957313.1,
XP_020957308.1,
XP_020957307.1,
XP_020957309.1,
XP_020957312.1,
XP_020957311.1
|
| Others |
UniGene:
Ssc.17246
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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