| Type | Description |
|---|---|
| Definition | matrix metallopeptidase 14 |
| Date | Results | Publications |
|---|---|---|
| 2013-03-16 12:23:00 | Modulation of MT1-MMP activity and microRNA-133a exportation into the myocardial interstitium occurred in the setting of acute myocardial ischemia-reperfusion. | 23102905 |
| 2011-01-15 11:05:00 | A heterogeneous response in MT1-MMP activity likely contributes to regional dysfunction with ischemia-reperfusion. Subsequent I/R activates a proteolytic cascade within the MI region, contributing to continued adverse remodeling. | 20935147 |
| 2010-01-21 00:00:00 | In an isolated left ventricular myocyte ischemia/reperfusion model, hypoxia induced a >70% increase in MT1-MMP abundance in myocytes. Confocal microscopy revealed MT1-MMP internalization during this time & reemergence to the membrane with reperfusion. | 15723986 |
| 2010-01-21 00:00:00 | Induction of endogenous MMP-14 gene and coexpression of SAF-1 & MMP-14 in the macrophages present in the atherosclerotic plaque implicate SAF-1 as a key regulator of MMP-14 gene induction in macrophage cells. | 15528467 |
| 2010-01-21 00:00:00 | PI3K-dependent regulation of MT1-MMP protein synthesis and subsequent activation of latent MMP-2 as critical events in neointimal hyperplasia after vascular injury. | 15297252 |
| Type | IDs |
|---|---|
| Synonymous | MT1-MMP |
| Gene |
UniProtKB-ID:
MMP14_PIG
UniprotKB:
Q9XT90
UniParc:
UPI000012F251
EMBL:
AF067419
KO:
ssc:397471
|
| Nucleutide sequences |
EMBL-CDS:
AAD38324.1
|
| Protein sequencees |
RefSeq:
NP_999404.2,
XP_020953962.1
|
| Others |
UniRef100:
UniRef100_Q9XT90
UniRef90:
UniRef90_P50281
UniRef50:
UniRef50_P50281
UniGene:
Ssc.734
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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