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397457 EDNRA

397457

EDNRA

endothelin receptor type A

protein-coding

Sus scrofa

基因描述

Type Description
Definition endothelin receptor type A

研究结论

Date Results Publications
2016-05-28 10:16:00 sub-vasomotor concentration of ET-1 leads to vascular dysfunction by impairing endothelium-dependent NO-mediated dilation via p38 kinase-mediated production of superoxide from NADPH oxidase following ETA receptor activation 26211713
2014-05-24 11:17:00 PDE5 inhibition and increase in cGMP produce pulmonary vasodilation that is mediated in part through inhibition of the ET pathway, thereby precluding an additional vasodilator effect of ETA/ETB receptor blockade in the presence of PDE5 inhibition. 24414253
2012-12-08 10:02:00 Blocking ET(A) and ET(B) receptors partially protects sinusoidal circulation and tissue oxygenation against stress induced by high intra-abdominal pressure (IAP). 22908974
2012-05-12 11:12:00 Dual endothelin receptor blockade with tezosentan attenuates hypoxia-induced pulmonary vasoconstriction in porcine model. 21726419
2011-10-15 10:53:00 These results suggest that endothelin released during endotoxemia acts via endothelin A receptors to impair renal medullary blood flow causing ischemia. 21760895

名称对应

Type IDs
Gene
UniProtKB-ID: EDNRA_PIG
UniprotKB: Q29010
UniParc: UPI000012A212
EMBL: S80652
Ensembl: ENSSSCG00065013180, ENSSSCG00005029450, ENSSSCG00030017166, ENSSSCG00015045817, ENSSSCG00045022387, ENSSSCG00050026780, ENSSSCG00055021336, ENSSSCG00040075833, ENSSSCG00060002008
KO: ssc:397457
Nucleutide sequences
EMBL-CDS: AAB36014.1
Ensembl_TRS: ENSSSCT00055042022, ENSSSCT00040105368, ENSSSCT00060002446, ENSSSCT00015061597, ENSSSCT00030023764, ENSSSCT00050036077, ENSSSCT00045038265, ENSSSCT00005046976, ENSSSCT00065017565
Protein sequencees
Ensembl_PRO: ENSSSCP00040048224, ENSSSCP00060000769, ENSSSCP00050014996, ENSSSCP00065007180, ENSSSCP00055033461, ENSSSCP00030010662, ENSSSCP00005028915, ENSSSCP00015024741, ENSSSCP00045026586
RefSeq: XP_020956134.1, XP_020956135.1, NP_999394.1
Others
UniRef100: UniRef100_Q29010
UniRef90: UniRef90_P26684
UniRef50: UniRef50_P26684
UniGene: Ssc.16189

全选

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