Type | Description |
---|---|
Definition | melanocortin 4 receptor |
Date | Results | Publications |
---|---|---|
2020-12-19 13:39:00 | The Asp298Asn polymorphism of melanocortin-4 receptor (MC4R) in pigs: evidence for its potential effects on MC4R constitutive activity and cell surface expression. | 32738077 |
2020-07-18 10:35:00 | Deletion of MC4R results in hyperphagia and increased body fat, ultimately leading to hepatic steatosis without atherogenic diet. Minipigs lacking MC4R exhibited hyperorexia, insulin resistance, hyperinsulinemia, disordered lipid metabolism and their livers accumulated significant amounts of fat. | 31629472 |
2016-02-13 12:49:00 | These results indicate that genetic selection against boar taint is possible using MC4R as a marker. | 26020871 |
2015-04-11 13:22:00 | These results suggest that LEPR, MC4R, PIK3C3 and VRTN are useful markers for accurately predicting breeding values in Duroc pigs. | 24128088 |
2015-01-03 11:37:00 | Transcriptional profiling was used to identify genes and pathways that responded to intracerebroventricular injection of MC4R agonist [Nle(4), d-Phe(7)]-alpha-melanocyte stimulating hormone in pigs homozygous for the missense mutation in the MC4R. | 20215418 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
MC4R_PIG
UniprotKB:
O97504
UniParc:
UPI000012ED4E
EMBL:
AF087937,
AF227727,
AB021664,
DQ388767
Ensembl:
ENSSSCG00000051798
KO:
ssc:397359
|
Nucleutide sequences |
EMBL-CDS:
BAA36170.1,
AAF34778.1,
ABD28176.1,
AAF31753.1
Ensembl_TRS:
ENSSSCT00000091644
|
Protein sequencees |
Ensembl_PRO:
ENSSSCP00000074588
RefSeq:
NP_999338.1
|
Others |
UniRef100:
UniRef100_O97504
UniRef90:
UniRef90_P32245
UniRef50:
UniRef50_P32245
UniGene:
Ssc.16081
|
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