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397359 MC4R

397359

MC4R

melanocortin 4 receptor

protein-coding

Sus scrofa

基因描述

Type Description
Definition melanocortin 4 receptor

研究结论

Date Results Publications
2020-12-19 13:39:00 The Asp298Asn polymorphism of melanocortin-4 receptor (MC4R) in pigs: evidence for its potential effects on MC4R constitutive activity and cell surface expression. 32738077
2020-07-18 10:35:00 Deletion of MC4R results in hyperphagia and increased body fat, ultimately leading to hepatic steatosis without atherogenic diet. Minipigs lacking MC4R exhibited hyperorexia, insulin resistance, hyperinsulinemia, disordered lipid metabolism and their livers accumulated significant amounts of fat. 31629472
2016-02-13 12:49:00 These results indicate that genetic selection against boar taint is possible using MC4R as a marker. 26020871
2015-04-11 13:22:00 These results suggest that LEPR, MC4R, PIK3C3 and VRTN are useful markers for accurately predicting breeding values in Duroc pigs. 24128088
2015-01-03 11:37:00 Transcriptional profiling was used to identify genes and pathways that responded to intracerebroventricular injection of MC4R agonist [Nle(4), d-Phe(7)]-alpha-melanocyte stimulating hormone in pigs homozygous for the missense mutation in the MC4R. 20215418

名称对应

Type IDs
Gene
UniProtKB-ID: MC4R_PIG
UniprotKB: O97504
UniParc: UPI000012ED4E
EMBL: AF087937, AF227727, AB021664, DQ388767
Ensembl: ENSSSCG00000051798
KO: ssc:397359
Nucleutide sequences
EMBL-CDS: BAA36170.1, AAF34778.1, ABD28176.1, AAF31753.1
Ensembl_TRS: ENSSSCT00000091644
Protein sequencees
Ensembl_PRO: ENSSSCP00000074588
RefSeq: NP_999338.1
Others
UniRef100: UniRef100_O97504
UniRef90: UniRef90_P32245
UniRef50: UniRef50_P32245
UniGene: Ssc.16081

全选

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研究热度

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