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3973 LHCGR

3973

LHCGR

luteinizing hormone/choriogonadotropin receptor

protein-coding

Homo sapiens

基因描述

Type Description
Definition luteinizing hormone/choriogonadotropin receptor

研究结论

Date Results Publications
2021-03-13 13:25:00 Reduced Gonadotrophin Receptor Expression Is Associated with a More Aggressive Ovarian Cancer Phenotype. 33374698
2020-08-29 12:49:00 Candidate genes for age at menarche are associated with endometrial hyperplasia. 32640302
2020-06-27 12:18:00 Of the 15 variants, 3 variants (rs13405728 in LHCGR; rs13429458 in THADA and rs2209972 IDE genes) were found to be associated with PCOS. The association was successfully replicated in an independent cohort. Insilico analysis categorized two variants (rs13429458-THADA and rs2209972-IDE genes) as deleterious. 32416252
2020-06-06 13:48:00 High expression of LHCGR is associated with Polycystic ovary syndrome. 31276164
2020-06-06 13:16:00 The expression of LH-R mRNA has a positive correlation with oocyte quality in poor responder patients and a negative correlation in non-poor responders. Our study suggests an optimal expression of LH- R mRNA in granulosa cells during controlled ovarian stimulation to obtain good quality oocytes 31131092

名称对应

Type IDs
Synonymous HHG, LCGR, LGR2, LH/CG-R, LH/CGR, LHR, LHRHR, LSH-R, ULG5
Gene
UniProtKB-ID: LSHR_HUMAN
UniprotKB: P22888
UniParc: UPI0001BE80D1, UPI000013E1E1
EMBL: X84763, AC073082, AF082076, X84757, AF024642, X84758, X84753, AC087816, X84754, X84762, M73746, X84756, X84761, M63108, X84755, X84760, S57793, X84759
Ensembl: ENSG00000138039
KO: hsa:3973
Nucleutide sequences
EMBL-CDS: AAA70231.1, AAB19917.2, AAB88417.1, AAA59515.1, AAC98291.1, CAA59234.1
Ensembl_TRS: ENST00000294954
Protein sequencees
Ensembl_PRO: ENSP00000294954
RefSeq: XP_016859579.1, XP_016859578.1, XP_006712078.1, XP_011531136.1, NP_000224.2, XP_005264366.1, XP_011531133.1
Others
UniRef100: UniRef100_P22888
UniRef90: UniRef90_P22888
UniRef50: UniRef50_P16235
UniGene: Hs.468490
CCDS: CCDS1842.1

全选

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研究热度

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