| Type | Description |
|---|---|
| Definition | commissureless |
| Date | Results | Publications |
|---|---|---|
| 2017-09-23 10:21:00 | PRRG4 could re-localize hRobo1 from the cell surface, suggesting that PRRG4 is a functional homologue of Comm. Comm is required for axon guidance and synapse formation in the fly, so PRRG4 could contribute to the autistic symptoms of WAGR by disturbing either of these processes in the developing human brain. | 28859078 |
| 2010-01-21 00:00:00 | Axon guidance by robo is regulated by Comm which inhibits Robo signaling by promoting the sorting of Robo into the endocytic pathway | 12361590 |
| 2010-01-21 00:00:00 | These studies provide insights into the specific regulation of dNedd4-mediated ubiquitination of Comm and subsequent internalization of Comm or the Comm/Roundabout complex, critical for CNS and muscle development. | 16531238 |
| 2010-01-21 00:00:00 | dNedd4 and ubiquitination are required for Commissureless endocytosis and proper neuromuscular synaptogenesis. | 17074801 |
| 2010-01-21 00:00:00 | findings show Fra mediates canonical chemoattraction in response to netrin & it functions independently of netrin to activate commissureless transcription, allowing attraction to be coupled to downregulation of repulsion in precrossing commissural axons | 19325078 |
| Type | IDs |
|---|---|
| Synonymous | CG17943, Comm, Dmel\CG17943 |
| Gene |
UniProtKB-ID:
COMM_DROME,
D5A7L2_DROME
UniprotKB:
Q24139,
D5A7L2
UniParc:
UPI00001246FD
EMBL:
AE014296,
BT122139,
U35854
EnsemblGenome:
FBgn0010105
KO:
dme:Dmel_CG17943
|
| Nucleutide sequences |
EMBL-CDS:
AAF49584.1,
AAC47019.1,
ADE21082.1,
AGB94584.1
Gene_ORFName:
CG17943,
Dmel_CG17943,
CG17943
EnsemblGenome_TRS:
FBtr0075579,
FBtr0333023,
FBtr0075579,
FBtr0333023
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0305237,
FBpp0075332,
FBpp0075332,
FBpp0305237
RefSeq:
NP_001261891.1,
NP_524095.1
|
| Others |
UniRef100:
UniRef100_Q24139
UniRef90:
UniRef90_Q24139
UniRef50:
UniRef50_Q24139
UniGene:
Dm.2546
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员