DUOX2 - dual oxidase 2-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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397060 DUOX2

基因描述

Type	Description
Definition	dual oxidase 2

研究结论

Date	Results	Publications
2017-12-02 10:54:00	A novel recessive c.1226A>G transition of the dual oxidase 2 gene was identified as the causative mutation for a severe congenital hypothyroidism model together with anemia and T lymphopenia which mimics the clinical features of hypothyroid patients	28972010
2010-01-21 00:00:00	the dual oxidase 2 N-terminal region is targeted to the plasma membrane	15150274
2010-01-21 00:00:00	Expression along the length of the gastrointestinal tract.	15591162

名称对应

Type	IDs
Gene	UniProtKB-ID: DUOX2_PIG UniprotKB: Q8HZK2 UniParc: UPI000042AF33 EMBL: AF181973, AF547267 KO: ssc:397060
Nucleutide sequences	EMBL-CDS: AAF20056.1, AAN39339.2
Protein sequencees	RefSeq: NP_999164.2, XP_020938217.1
Others	UniRef100: UniRef100_Q8HZK2 UniRef90: UniRef90_Q8HZK2 UniRef50: UniRef50_Q9NRD8 UniGene: Ssc.33

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
28972010	Thyroid hormone regulates hematopoiesis via the TR-KLF9 axis. Blood Ying Zhang , Yuanyuan Xue , Chunwei Cao , Jiaojiao Huang , Qianlong Hong , Tang Hai , Qitao Jia , Xianlong Wang , Guosong Qin , Jing Yao , Xiao Wang , Qiantao Zheng , Rui Zhang , Yongshun Li , Ailing Luo , Nan Zhang , Guizhi Shi , Yanfang Wang , Hao Ying , Zhonghua Liu , Hongmei Wang , Anming Meng , Qi Zhou , Hong Wei , Feng Liu , Jianguo Zhao	2017-11-16	-
17145712	PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Nucleic Acids Res. Hirohide Uenishi , Tomoko Eguchi-Ogawa , Hiroki Shinkai , Naohiko Okumura , Kohei Suzuki , Daisuke Toki , Noriyuki Hamasima , Takashi Awata	2007-01-01	SPARCL1, SLA-3, DYNC1H1, SLA-1, P4HA1, DNMT3A, CPE, TNFRSF1B, SLA-DQB1, CD14, APOBEC3F, PDE4B, KCND3, KCNIP2, UIMC1, C9, C8A, C8G, SEPP1, LOC100037968, SLC7A7, PET100, TOMM7, NDUFC1, SLIRP, LOC100037988, COX6C, COX7C, NDUFV2, PSMB7, RPL10A, RPL14, RPL27, RPS21, TMSB10, ATPIF1, RCHY1, CD1E, SEP15, CCL11, CD72, COX6B, RPL4, EIF4E, LGALS3, SNRPE, ZFAND5, SDHD, C5AR1, ABCG8, CYB561, GNAS, RBM39, BRCA1, KRT2, HPS4, BLOC1S5, BLOC1S6, PNPLA3, SRGN, SPTAN1, BIRC6, HPS5, AMPD1, MMP12, MYOT, COL6A3, EIF4E2, PPP2R5A, IFIH1, EIF4A2, EIF4A1, SQLE, CYP39A1, ALG2, BPIFB2, BPIFB5, CYP4F2, SLC44A4, DXO, NIFK, CD1D, SNCG, LNPEP, MUC13, COPS5, SIRT2, SIRT3, RBM38, ANGPTL2, STC2, AQP4, LASS6, CD302, CYP3A46, KRT18, PEX6, CNPY3, MEA1
15972824	Dual oxidase-2 has an intrinsic Ca2+-dependent H2O2-generating activity. J Biol Chem Rabii Ameziane-El-Hassani , Stanislas Morand , Jean-Luc Boucher , Yves-Michel Frapart , DaphnÃ© Apostolou , Diane Agnandji , SÃ©dami Gnidehou , RenÃ©e Ohayon , Marie-Sophie NoÃ«l-Hudson , Jacques Francon , Khalid Lalaoui , Alain Virion , Corinne Dupuy	2005-08-26	-
15591162	Dual oxidase2 is expressed all along the digestive tract. Am. J. Physiol. Gastrointest. Liver Physiol. Rabii Ameziane El Hassani , Nesrine Benfares , Bernard Caillou , Monique Talbot , Jean-Christophe Sabourin , Virginie Belotte , Stanislas Morand , SÃ©dami Gnidehou , Diane Agnandji , RenÃ©e Ohayon , Jacques Kaniewski , Marie-Sophie NoÃ«l-Hudson , Jean-Michel Bidart , Martin Schlumberger , Alain Virion , Corinne Dupuy	2005-05-01	DUOX2, DUOX2
15150274	Targeting of the dual oxidase 2 N-terminal region to the plasma membrane. J Biol Chem Stanislas Morand , Diane Agnandji , Marie-Sophie Noel-Hudson , ValÃ©rie Nicolas , Sandrine Buisson , Laetitia Macon-Lemaitre , SÃ©dami Gnidehou , Jacques Kaniewski , RenÃ©e Ohayon , Alain Virion , Corinne Dupuy	2004-07-16	-
14681463	PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Nucleic Acids Res. Hirohide Uenishi , Tomoko Eguchi , Kohei Suzuki , Tetsuya Sawazaki , Daisuke Toki , Hiroki Shinkai , Naohiko Okumura , Noriyuki Hamasima , Takashi Awata	2004-01-01	PIK3R6, DESI2, ENPP1, SPARCL1, NREP, SLA-3, IRF7, DYNC1H1, SLA-1, P4HA1, DNMT3A, SEPHS2, SGMS1, CPE, BIN1, TNFRSF1B, SLA-DQB1, CD14, APOBEC3F, PDE4B, KCND3, KCNIP2, UIMC1, LOC100037950, C9, C6, C8A, C8B, C8G, LOC100037957, CAPZA2, CTSB, SEPP1, LOC100037968, SLC7A7, C2H19orf70, ATP5J2, PET100, TOMM7, NDUFC1, SLIRP, LOC100037988, COX6C, COX7C, NDUFV2, PSMB7, RPL10A, RPL14, RPL27, RPS21, RPS26, TMSB10, TPM1, ATPIF1, KLF7, RCHY1, PCD1B, CD1E, SEP15, CCL11, CD72, PVRL2, COX6B, RPS6, CLEC7A, RPL4, EIF4E, LGALS3, SNRPE, ZFAND5, ADSS, SDHD, C5AR1, BTG3, GNA14, NAGS, TNMD, ABCG8, YWHAQ, PGRMC2, CYB561, CNN3, GNAS, RBM39, BRCA1, EDN3, KRT2, HPS4, BLOC1S5, BLOC1S6, RABGGTA, MLPH, ATP7B, CRYZL1, PNPLA3, SRGN, SPTAN1, BIRC6, HPS5
12639906	Effect of iodide on nicotinamide adenine dinucleotide phosphate oxidase activity and Duox2 protein expression in isolated porcine thyroid follicles. Endocrinology Stanislas Morand , Mokhtar Chaaraoui , Jacques Kaniewski , Danielle DÃ¨me , RenÃ©e Ohayon , Marie Sophie Noel-Hudson , Alain Virion , Corinne Dupuy	2003-04-01	DUOX2, DUOX1
12538618	Identification of a truncated dual oxidase 2 (DUOX2) messenger ribonucleic acid (mRNA) in two rat thyroid cell lines. Insulin and forskolin regulation of DUOX2 mRNA levels in FRTL-5 cells and porcine thyrocytes. Endocrinology Stanislas Morand , Orquidea Filipe Dos Santos , RenÃ©e Ohayon , Jacques Kaniewski , Marie-Sophie Noel-Hudson , Alain Virion , Corinne Dupuy	2003-02-01	Duox1, Duox2, DUOX2
10601291	Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cdnas. J Biol Chem C Dupuy , R Ohayon , A Valent , M S NoÃ«l-Hudson , D DÃ¨me , A Virion	1999-12-24	-

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