| Type | Description |
|---|---|
| Definition | cytidine monophosphate-N-acetylneuraminic acid hydroxylase |
| Date | Results | Publications |
|---|---|---|
| 2018-01-06 12:28:00 | Silencing the GGTA1, CMAH and B4GalNT2 genes in pigs achieved a significant antigen reduction. Changing the porcine carbohydrate profile effectively mediates human antibody-mediated complement dependent cytoxicity. | 27100221 |
| 2017-05-27 11:34:00 | Many waitlisted renal transplant patients have minimal xenoreactive antibody binding to the GGTA1/CMAH/B4GalNT2 knockout pig, but some HLA antibodies in sensitized patients cross-react with class I SLA. | 28114170 |
| 2016-07-16 10:11:00 | Silencing the porcine CMAH/GGTA1 genes necessary to avoid antibody-mediated rejection in a pig-to-human model also reduces the xenogeneic consumption of human platelets by the porcine liver. | 26906939 |
| 2015-04-25 12:33:00 | GGTA1/CMAH knockout pig samples had increased relative amounts of high-mannose, incomplete, and xylosylated N-linked glycans | 24033743 |
| 2012-09-08 10:59:00 | Report cloning of cytidine monophospho-N-acetylneuraminic acid hydroxylase from porcine endothelial cells. | 22564646 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
A8WAC5_PIG
UniprotKB:
A8WAC5
UniParc:
UPI00015E501C
EMBL:
EU204974
KO:
ssc:396918
|
| Nucleutide sequences |
EMBL-CDS:
ABW80749.1
|
| Protein sequencees |
RefSeq:
NP_001106486.1
|
| Others |
UniRef100:
UniRef100_A8WAC5
UniRef90:
UniRef90_Q61419
UniRef50:
UniRef50_Q61419
UniGene:
Ssc.14511
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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