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3963 LGALS7

3963

LGALS7

galectin 7

protein-coding

Homo sapiens

基因描述

Type Description
Definition galectin 7

研究结论

Date Results Publications
2021-02-27 13:45:00 Pro4 prolyl peptide bond isomerization in human galectin-7 modulates the monomer-dimer equilibrum to affect function. 32766716
2020-10-03 12:57:00 A potential contribution of decreased galectin-7 expression in stratified epithelia to the development of cutaneous and oesophageal manifestations in systemic sclerosis. 30739341
2020-05-23 11:52:00 Gal-7 knockdown attenuates TGF-beta1-induced apoptosis in bronchial epithelial cells through inactivation of JNK pathway. 30594507
2019-08-31 13:24:00 Herein, the authors first revealed that Galectin-7 was one of the Tid1-interacting client proteins. An inverse association of protein expression profile between Tid1 and Galectin-7 was determined in head and neck squamous cell carcinoma patients. Low Tid1 and high Galectin-7 expression predicted poor overall survival in head and neck squamous cell carcinoma. 30083263
2018-04-28 11:18:00 We further demonstrated using the NMR-based hydrogen-deuterium exchange (HDX) that lactose binding increases the exchange rates of residues located on the opposite side of the ligand-binding pocket for hGal1 and hGal8(NTD), indicative of allostery. Additionally, lactose binding induces significant stabilisation of hGal8(CTD) across the entire domain 28813004

名称对应

Type IDs
Synonymous GAL7, LGALS7A
Gene
UniProtKB-ID: LEG7_HUMAN
UniprotKB: P47929
UniParc: UPI000000D9FF
EMBL: CR456917, U06643, L07769, BC061588, CH471126, BC042911, BC073743
Ensembl: ENSG00000178934, ENSG00000205076, ENSG00000282902, ENSG00000283082
KO: hsa:3963, hsa:653499
Nucleutide sequences
EMBL-CDS: AAH42911.2, EAW56818.1, EAW56817.1, CAG33198.1, AAH73743.1, AAH61588.1, AAA86820.1, AAA67899.1
Ensembl_TRS: ENST00000634800, ENST00000378626, ENST00000314980, ENST00000634448
Protein sequencees
Ensembl_PRO: ENSP00000489395, ENSP00000367891, ENSP00000313571, ENSP00000489582
RefSeq: NP_002298.1
Others
UniRef100: UniRef100_P47929
UniRef90: UniRef90_P47929
UniRef50: UniRef50_P47929
UniGene: Hs.702546
CCDS: CCDS42565.1

全选

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