| Type | Description |
|---|---|
| Definition | paired like homeodomain 2 |
| Date | Results | Publications |
|---|---|---|
| 2015-08-15 11:14:00 | Pitx2 is essential for axis formation, and that it acts as a direct regulator of cVg1 expression by binding to enhancers within neighbouring genes. | 25496870 |
| 2015-03-21 10:12:00 | Pitx2 pathway drives organ-specific arterial and lymphatic development in the intestine | 25482882 |
| 2011-09-03 11:11:00 | Downregulation of PITX2 and LEF1 genes may interfere with ventral body wall formation in Cd chick model causing omphalocele by disrupting somite myogenesis. | 21259014 |
| 2010-03-01 11:59:00 | Wnt/Lef1 signaling regulates epaxial myogenesis via Pitx2. | 19850024 |
| 2010-01-21 12:36:00 | Data suggest that the Pitx2c N-terminal domain competes with endogenous Pitx2c for binding to a protein interaction partner that is required for the activation of genes that direct asymmetric morphogenesis along the left-right axis. | 19681163 |
| Type | IDs |
|---|---|
| Synonymous | Ptx2 |
| Gene |
UniProtKB-ID:
PITX2_CHICK
UniprotKB:
O93385
UniParc:
UPI000002B121,
UPI0000131B4C
EMBL:
AF063935,
AF077092,
AF076640
KO:
gga:395862
|
| Nucleutide sequences |
EMBL-CDS:
AAC18346.1,
AAC27322.1,
AAD46097.1
|
| Protein sequencees |
RefSeq:
XP_025005283.1,
XP_025005284.1,
NP_990341.1
|
| Others |
UniRef100:
UniRef100_O93385
UniRef90:
UniRef90_O93385
UniRef50:
UniRef50_Q99697-2
UniGene:
Gga.3398
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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