| Type | Description |
|---|---|
| Definition | topoisomerase (DNA) II alpha |
| Date | Results | Publications |
|---|---|---|
| 2017-09-02 12:56:00 | Both the genome instability and cell death of MRE11-null and MRE11-mutated H129N cells are significantly reversed by overexpression of Tdp2, an enzyme that eliminates covalent Top2 conjugates; thus, the essential role of Mre11 nuclease activity is likely to remove the DNA lesions. | 27814490 |
| 2016-05-14 11:04:00 | PICH and Topo II cooperate to prevent chromosome missegregation events in mitosis. | 26643143 |
| 2013-02-23 11:24:00 | The topoisomerase IIalpha contributed to shaping mitotic chromosomes by promoting the shortening of the chromatid axes and apparently acting in opposition to the actions of KIF4 and condensins. | 23166350 |
| 2006-09-11 09:23:00 | found in chicken chromosome scaffolds. Chicken topoisomerase II is located in the neucleus, associated with mitotic chromosomes and chromosome scaffolds. | 2985625 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
TOP2A_CHICK
UniprotKB:
O42130
UniParc:
UPI0000137193
EMBL:
AB007445
KO:
gga:395570
|
| Nucleutide sequences |
EMBL-CDS:
BAA22539.2
|
| Protein sequencees |
RefSeq:
NP_990122.1
|
| Others |
UniRef100:
UniRef100_O42130
UniRef90:
UniRef90_O42130
UniRef50:
UniRef50_O42130
UniGene:
Gga.2010
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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