| Type | Description |
|---|---|
| Definition | Dynactin 1, p150 subunit |
| Date | Results | Publications |
|---|---|---|
| 2019-03-30 10:07:00 | artificially dimerized Egl activates dynein-dynactin-BicD in the absence of mRNA. The ability of mRNA cargo to orchestrate the activation of the mRNP (messenger ribonucleotide protein) complex is an elegant way to ensure that only cargo-bound motors are motile. | 29944116 |
| 2019-03-30 10:07:00 | the RNA is required for robust activation of dynein motility. We show that a cis-acting RNA localisation signal promotes the interaction of Egl with BicD, which licenses the latter protein to recruit dynein and dynactin. Our data support a model for BicD activation based on RNA-induced occupancy of two Egl-binding sites on the BicD dimer. | 29944118 |
| 2013-12-21 12:07:00 | Arfaptin physically associates with Glued and other dynactin complex components in the nervous system of both flies and mice and colocalizes with Glued at the Golgi in motor neurons. | 23596322 |
| 2013-11-30 12:36:00 | It uncovered an important requirement for Lis1 in promoting the recruitment of dynein and its accessory complex dynactin to RNA localization complexes. | 23918939 |
| 2010-01-21 00:00:00 | We conclude that Lis1/dynactin act together to regulate multiple, independent functions in mitotic cells, including spindle formation and cell cycle checkpoint release. | 16107559 |
| Type | IDs |
|---|---|
| Synonymous | CG9206, DCTN1, DYNA_DROME, Dmel\CG9206, FCP-D, Gl, Glu, Glued, P150, P150A, P150[Glued], gl, p150, p150/Glued, p150/glued, p150[Glued], p150[glued], t1 |
| Gene |
UniProtKB-ID:
DCTN1_DROME
UniprotKB:
P13496
UniParc:
UPI00001249B3
EMBL:
J02932,
AY118377,
BT044559,
AE014296
EnsemblGenome:
FBgn0001108
KO:
dme:Dmel_CG9206
|
| Nucleutide sequences |
EMBL-CDS:
AAM48406.1,
AAF49788.1,
ACI15754.1
Gene_ORFName:
CG9206
EnsemblGenome_TRS:
FBtr0075756
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0075498
RefSeq:
NP_524061.1
|
| Others |
UniRef100:
UniRef100_P13496
UniRef90:
UniRef90_P13496
UniRef50:
UniRef50_P13496
UniGene:
Dm.12980
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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