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395313 MX1

395313

MX1

MX dynamin like GTPase 1

protein-coding

Gallus gallus

基因描述

Type Description
Definition MX dynamin like GTPase 1

研究结论

Date Results Publications
2015-02-14 11:40:00 Data indicate that the expression levels of chick fibroblast DF-1 interferon beta (IFN-beta) and myxovirus resistance-1 (Mx1) mRNA were down-regulated by over-expression of duck albumin (ALB) gene. 25200153
2013-05-18 12:02:00 These results demonstrated that a single amino acid polymorphism at 631 aa of the chicken Mx protein altered both the antiviral activity and intracellular localization. 23201406
2013-01-26 10:19:00 The current study provides valuable information on the effect of the Mx1 gene on the genetic resistance to avian influenza virus in chickens, and Mx1 will not be applicable for enhancing genetic resistance to AIV infection in chickens. 23155008
2011-10-08 12:04:00 the antiviral effect of type I IFN in chicken cells was not dependent on Mx, and both isoforms of chicken Mx protein appear to lack GTPase activity 21632756
2011-07-09 10:05:00 Following intranasal infection with HPAIV strain A/Chicken/Queretaro/14588-19/1995 H5N2, chickens homozygous for Asn631 allele were significantly more resistant to disease based on early mortality, morbidity, or virus shedding than Ser631 homozygotes. 21286706

名称对应

Type IDs
Synonymous GTPase, MX
Gene
UniProtKB-ID: MX_CHICK
UniprotKB: Q90597
UniParc: UPI000012FAB7
EMBL: AB088535, DQ788613, Z23168, AB088536, DQ788615, AB088534, AB244818, AB088533, DQ788614, DQ788616
KO: gga:395313
Nucleutide sequences
EMBL-CDS: ABH07790.1, ABH07789.1, BAF30836.1, ABH07791.1, BAC06349.1, BAC06348.1, ABH07788.1, BAC06347.1, CAA80686.1, BAC06346.1
Protein sequencees
RefSeq: NP_989940.1
Others
UniRef100: UniRef100_Q90597
UniRef90: UniRef90_Q90597
UniRef50: UniRef50_Q90597
UniGene: Gga.131

全选

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研究热度

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