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3950 LECT2

3950

LECT2

leukocyte cell derived chemotaxin 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition leukocyte cell derived chemotaxin 2

研究结论

Date Results Publications
2021-03-20 13:28:00 Down-regulation of LECT2 promotes osteogenic differentiation of MSCs via activating Wnt/beta-catenin pathway. 32763823
2020-12-19 13:43:00 Plasma half-life and tissue distribution of leukocyte cell-derived chemotaxin 2 in mice. 32764719
2020-06-20 10:36:00 This study reports novel findings on the important role of LECT2/Tie1 signaling in pathogenesis of liver fibrosis and the underlying mechanisms. The serum LECT2 level may represent a potential diagnostic marker for liver fibrosis, and more importantly, LECT2 may serve as a potential therapeutic target for liver fibrosis. 31474362
2020-06-13 10:23:00 Data indicate the explicit amyloidogenic core of human leukocyte chemotactic factor 2 (LECT2) and pinpoints regions with distinct amyloidogenic properties. 31170474
2018-12-22 10:45:00 Overexpression of LECT2 or treatment with a recombinant LECT2 protein impaired the colony-forming ability and motility of non-small cell lung cancer cells harboring high levels of activated EGFR and MET. 30453282

名称对应

Type IDs
Synonymous chm-II, chm2
Gene
UniProtKB-ID: LECT2_HUMAN
UniprotKB: O14960
UniParc: UPI000013DA0F
EMBL: D63521, AB007546, BC093670, BC101579, AK314092, AC002428, AC004763
Ensembl: ENSG00000145826
KO: hsa:3950
Nucleutide sequences
EMBL-CDS: AAI01580.1, BAA25669.1, AAH93670.1, AAC17734.1, BAA23609.1, BAG36787.1, AAB66905.1
Ensembl_TRS: ENST00000274507
Protein sequencees
Ensembl_PRO: ENSP00000274507
RefSeq: NP_002293.2
Others
UniRef100: UniRef100_O14960
UniRef90: UniRef90_O14960
UniRef50: UniRef50_O14960
UniGene: Hs.512580
CCDS: CCDS4190.1

全选

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研究热度

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