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3945 LDHB

3945

LDHB

lactate dehydrogenase B

protein-coding

Homo sapiens

基因描述

Type Description
Definition lactate dehydrogenase B

研究结论

Date Results Publications
2020-10-03 12:54:00 Diagnostic value of procalcitonin, C-reactive protein and lactate dehydrogenase in paediatric malignant solid tumour concurrent with infection and tumour progression. 30976022
2020-03-21 10:53:00 Study demonstrated that miR-335-5p regulates cell proliferation, migration as well as invasion of CRC cells through down-regulating LDHB 31424671
2019-12-21 11:17:00 SIRT5-induced deacetylation of LDHB triggers hyperactivation of autophagy, a key event in tumorigenesis. 30443978
2019-12-14 10:16:00 These results suggest that LDHB suppression is a key mechanism that enhances glycolysis and is critically involved in the maintenance and propagation of mitochondrial dysfunction via lactate release in liver cancer progression. 30923124
2019-09-28 11:41:00 Our results indicate that ectopic FGFR1 expression reprograms the energy metabolism of prostate cancer cells, representing a hallmark change in prostate cancer progression. FGF signaling drives the Warburg effect through differential regulation of LDHA and LDHB, thereby promoting the progression of prostate cancer 29891507

名称对应

Type IDs
Synonymous HEL-S-281, LDH-B, LDH-H, LDHBD, TRG-5
Gene
UniProtKB-ID: LDHB_HUMAN, A0A5F9ZHM4_HUMAN, Q5U077_HUMAN
UniprotKB: P07195, A0A5F9ZHM4, Q5U077
UniParc: UPI000013C8F6, UPI0001B34874
EMBL: HM005565, BC071860, X13795, BT019764, EU919185, BT019765, AK312328, X13796, X13799, AC010197, BC002362, Y00711, X13800, X13797, BC015122, X13794, AY189689, X13798, AC010185, EU794633, CH471094
Ensembl: ENSG00000111716
KO: hsa:3945
Nucleutide sequences
EMBL-CDS: CAA68701.1, AAH02362.1, AAH71860.1, CAA32033.1, AAH15122.1, EAW96449.1, ACF98331.1, AEE61162.1, ACJ13687.1, BAG35250.1, AAV38569.1, AAV38570.1, EAW96448.1, AAO85222.1
Gene_ORFName: hCG_24788
Ensembl_TRS: ENST00000350669, ENST00000396076, ENST00000673047
Protein sequencees
Ensembl_PRO: ENSP00000229319, ENSP00000379386, ENSP00000500484
RefSeq: NP_001167568.1, NP_002291.1, NP_001302466.1, XP_006719137.1
Others
UniRef100: UniRef100_A0A5F9ZHM4, UniRef100_P07195
UniRef90: UniRef90_P07195
UniRef50: UniRef50_P07195
UniGene: Hs.446149
CCDS: CCDS8691.1

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