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39443 Ptp69D

39443

Ptp69D

Protein tyrosine phosphatase 69D

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Protein tyrosine phosphatase 69D

研究结论

Date Results Publications
2018-06-23 10:29:00 The authors found that the depth of the final layer of stable photoreceptor axon termination relied primarily on the cumulative amount of LAR and Ptp69D cytoplasmic activity, while specific features of their ectodomains contribute to the choice between two synaptic layers, M3 and M6, in the medulla. 29116043
2017-06-24 10:08:00 the role of Slit and Robo receptors in wiring Drosophila higher-order brain circuits and identified differences in the cellular and molecular mechanisms of Robo/Slit function, was investigated. 27780041
2015-11-28 11:30:00 The single-growth-cone analysis suggests that Slit and RPTP69D are unlikely to influence axon sprouting, or branch initiation of mechanosensory-neurons, but rather control the selective consolidation and directed extension of midline-crossing axon branches. 26317474
2015-10-31 11:38:00 Mutations in the first Ig and catalytic domains disrupt synaptic terminal growth. PTP69D role in terminal growth is mechanistically distinct from axon targeting. 25433167
2010-01-21 00:00:00 indicate that mutations in Ptp69D resulting in axon guidance defects and lethality significantly compromise catalytic activity 16514605

名称对应

Type IDs
Synonymous 69D, CG10975, CT30751, DPTP, DPTP69D, Dmel\CG10975, Dptp69D, PTP69D, PTPase, Ptp, Ptp69d, R-PTP 69D, RPtp69D, dptp69D, dptp69d, ptp69D, ptp69d
Gene
UniProtKB-ID: PTP69_DROME
UniprotKB: P16620
UniParc: UPI00000800FC, UPI0000007345
EMBL: M27699, BT001531, AE014296
EnsemblGenome: FBgn0014007
KO: dme:Dmel_CG10975
Nucleutide sequences
EMBL-CDS: AAA28842.1, AAN71286.1, AAO41254.1, AAF49892.2
Gene_ORFName: CG10975
EnsemblGenome_TRS: FBtr0075914, FBtr0075913
Protein sequencees
EnsemblGenome_PRO: FBpp0075645, FBpp0075646
RefSeq: NP_788502.1, NP_524048.2
Others
UniRef100: UniRef100_P16620
UniRef90: UniRef90_P16620
UniRef50: UniRef50_P16620
UniGene: Dm.945

全选

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