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394 ARHGAP5

394

ARHGAP5

Rho GTPase activating protein 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition Rho GTPase activating protein 5

研究结论

Date Results Publications
2019-12-14 11:10:00 These results indicate that SIRT1 suppresses migration and invasion of gastric cancer by downregulating ARHGAP5 through an interaction with c-JUN, and these phenomena represent a novel mechanism of the antitumor action of SIRT1. 30250020
2017-08-12 11:59:00 only collagen-IV elicits the formation of proteolytically active podosomes through a mechanism involving increased Src phosphorylation, p190RhoGAP-B (also known as ARHGAP5) relocalisation and MT1-MMP (also known as MMP14) cell surface exposure at podosome sites. 27231093
2017-07-29 11:24:00 Brazilian Amerindian ancestry compared to Asian, European, and African Genomes.SNPs within or proximal to CIITA (rs6498115), SMC6 (rs1834619), and KLHL29 (rs2288697) were most differentiated in the Amerindian-specific branch. SNPs in ADAMTS9 (rs7631391), DOCK2 (rs77594147), SLC28A1 (rs28649017), ARHGAP5 (rs7151991), and CIITA (rs45601437) in the Asian comparison. 28100790
2016-04-09 10:03:00 This newly identified miR-744/ARHGAP5 pathway provides further insight into the progression and metastasis of NPC and indicates potential novel therapeutic targets for NPC. 25961434
2014-05-24 10:14:00 Ectopic expression of p190B suppressed the miR-494-induced EGFR upregulation. 24316134

名称对应

Type IDs
Synonymous GFI2, RhoGAP5, p190-B, p190BRhoGAP
Gene
UniProtKB-ID: RHG05_HUMAN
UniprotKB: Q13017
UniParc: UPI000057B85C, UPI000057B85B, UPI0000E01412, UPI00001FD3A9
EMBL: AB209751, BC075799, BC129929, AK292966, BC129928, BC032723, CH471078, BC050059, U17032
Ensembl: ENSG00000100852
KO: hsa:394
Nucleutide sequences
EMBL-CDS: BAD92988.1, AAH32723.1, AAH75799.1, EAW65935.1, AAI29930.1, AAA95963.1, BAF85655.1, AAH50059.1, EAW65936.1, EAW65937.1, AAI29929.1, EAW65938.1
Ensembl_TRS: ENST00000556611, ENST00000433497, ENST00000539826, ENST00000396582, ENST00000345122
Protein sequencees
Ensembl_PRO: ENSP00000371897, ENSP00000452222, ENSP00000441692, ENSP00000379827, ENSP00000407395
RefSeq: NP_001025226.1, XP_005267692.1, XP_016876777.1, NP_001164.2, XP_005267693.1
Others
UniRef100: UniRef100_Q13017
UniRef90: UniRef90_Q13017
UniRef50: UniRef50_Q13017
UniGene: Hs.592313
CCDS: CCDS45095.1, CCDS32062.1

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