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393845 pde6c

393845

pde6c

phosphodiesterase 6C, cGMP-specific, cone, alpha prime

protein-coding

Danio rerio

基因描述

Type Description
Definition phosphodiesterase 6C, cGMP-specific, cone, alpha prime

研究结论

Date Results Publications
2018-12-01 11:17:00 These observations illustrate the interdependence of cyclic GMP metabolism regulators between Aipl1, Pde6c, and Gc3 in photoreceptors. 28378769
2015-01-24 11:45:00 Collectively, these results demonstrate that the underlying mechanism of cone cell death in the pde6c(w59) mutant retina is through necroptosis, whereas rod photoreceptor bystander death occurs through a caspase-dependent mechanism. 24413151
2014-03-15 11:17:00 transient and Pde6-independent Ca(2+) elevations ('flashes') were detected throughout the inner segment and the synapse. 24030149
2010-01-21 00:00:00 We have identified a blind zebrafish mutant with rapid degeneration of cone photoreceptors caused by a mutation in the cone phosphodiesterase c (pde6c) gene, a key regulatory component in cone phototransduction. 18077698

名称对应

Type IDs
Synonymous zgc:73085
Gene
UniProtKB-ID: Q6P4P8_DANRE
UniprotKB: Q6P4P8
UniParc: UPI00002262AC
EMBL: BC063318
KO: dre:393845
Nucleutide sequences
EMBL-CDS: AAH63318.1
Protein sequencees
RefSeq: NP_957165.1
Others
UniRef100: UniRef100_Q6P4P8
UniRef90: UniRef90_A0A0R4IUY2
UniRef50: UniRef50_P35913
UniGene: Dr.117127

全选

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研究热度

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