| Type | Description |
|---|---|
| Definition | mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) |
| Date | Results | Publications |
|---|---|---|
| 2010-01-21 00:00:00 | Male mlh1 mutants are sterile and display an arrest in spermatogenesis at metaphase I, resulting in increased testis weight due to accumulation of prophase I spermatocytes. | 17237513 |
| 2010-01-21 00:00:00 | Identification and characterization of novel knockout mutants of the three major MMR genes, mlh1, msh2, and msh6, in zebrafish that develop tumors at low frequencies. | 18593904 |
| 2010-01-21 00:00:00 | In zebrafish mlh1 mutant (knock-out) males, a delay of both meiotic divisions occurs rather than complete arrest during meiosis I. Eggs fertilized with mutant sperm develop as malformed embryos and are aneuploid. | 18247060 |
| Type | IDs |
|---|---|
| Synonymous | zgc:66301 |
| Gene |
UniProtKB-ID:
Q6PFL1_DANRE
UniprotKB:
Q6PFL1
UniParc:
UPI00001CDF15
EMBL:
BC057507
KO:
dre:393632
|
| Nucleutide sequences |
EMBL-CDS:
AAH57507.1
|
| Protein sequencees |
RefSeq:
NP_956953.1,
XP_009305824.1
|
| Others |
UniRef100:
UniRef100_Q6PFL1
UniRef90:
UniRef90_B8A6F5
UniRef50:
UniRef50_P40692
UniGene:
Dr.77529
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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