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3936 LCP1

3936

LCP1

lymphocyte cytosolic protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition lymphocyte cytosolic protein 1

研究结论

Date Results Publications
2020-01-11 10:39:00 Among the proteins found to preferentially bind clasped rather than the isolated alphaM and beta2 subunits was L-plastin (LCP1, also known as plastin-2), which binds to and maintains the inactive state of alphaMbeta2 integrin in vivo and thereby regulates leukocyte adhesion to integrin ligands under flow. 30333137
2019-12-21 10:39:00 LPL oxidation diminishes its actin-bundling capacity. 31501427
2018-11-17 12:22:00 LCP1-positive oral squamous cell carcnome samples were correlated closely with the primary tumor size and regional lymph node metastasis. 28230172
2018-10-20 10:29:00 MOLP8/R cells display a very high overexpression of LCP1 gene (l-Plastin) controlled by HIF1&alpha. 29882856
2018-06-09 10:56:00 these findings support a plausible mechanism by which the AP4/L-plastin axis is regulated by the PI3K/AKT pathway in human prostate cancer (PCa)and may represent a novel therapeutic target in PCa treatment. 28981098

名称对应

Type IDs
Synonymous CP64, HEL-S-37, L-PLASTIN, LC64P, LPL, PLS2
Gene
UniProtKB-ID: PLSL_HUMAN, A0A024RDT4_HUMAN
UniprotKB: P13796, A0A024RDT4
UniParc: UPI00017A7DB2, UPI0000070B5C
EMBL: J02923, CH471075, AL137141, AK300556, BC010271, AH002870, BC007673, M34426, M22300, AK312393
Ensembl: ENSG00000136167
KO: hsa:3936
Nucleutide sequences
EMBL-CDS: BAG35310.1, EAX08757.1, BAG62262.1, AAH10271.1, AAA36184.1, AAA63236.1, AAH07673.1, AAB02845.1, AAA59529.1, EAX08758.1
Gene_ORFName: hCG_2020552
Ensembl_TRS: ENST00000398576, ENST00000323076
Protein sequencees
Ensembl_PRO: ENSP00000381581, ENSP00000315757
RefSeq: XP_005266431.1, NP_002289.2
Others
UniRef100: UniRef100_P13796
UniRef90: UniRef90_P13796
UniRef50: UniRef50_P13796
UniGene: Hs.381099, Hs.658408
CCDS: CCDS9403.1

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