| Type | Description |
|---|---|
| Definition | interferon regulatory factor 6 |
| Date | Results | Publications |
|---|---|---|
| 2017-10-14 11:38:00 | Here, we demonstrate the protein functions of human IRF6 missense gene variants could be rapidly assessed in detail by their abilities to rescue the irf6 -/- phenotype in zebrafish through variant mRNA microinjections at the one-cell stage. | 28945736 |
| 2017-03-11 11:39:00 | Fish IRF6 is distinguished from the homolog of mammals by being a positive regulator of IFN transcription and phosphorylated by MyD88 and TBK1, suggesting that differences in the IRF6 regulation pattern exist between lower and higher vertebrates. | 27577537 |
| 2016-12-17 11:18:00 | Authors report that Kruppel-like factor 17 (Klf17), like Grhl3, acts downstream of Irf6 in this network in zebrafish periderm. | 26692521 |
| 2013-04-06 13:05:00 | In zebrafish periderm, grainyhead-like 3 (grhl3) (an ancient regulator of the epidermal permeability barrier), was identified as acting downstream of Irf6. Simultaneous inhibition of grhl1 and grhl3 disrupted periderm differentiation in zebrafish. | 22931925 |
| 2010-01-21 00:00:00 | These experiments reveal a conserved role for maternally-encoded Irf6 in differentiation of a simple epithelium in X. laevis and D. rerio. | 19013452 |
| Type | IDs |
|---|---|
| Synonymous | zgc:63500 |
| Gene |
UniProtKB-ID:
Q6PGZ7_DANRE
UniprotKB:
Q6PGZ7
UniParc:
UPI00001CDDED
EMBL:
AY857643,
BC056772,
CU570769,
AH014791,
AY725802
Ensembl:
ENSDARG00000101986
KO:
dre:393570
|
| Nucleutide sequences |
EMBL-CDS:
AAX57954.1,
AAH56772.1,
AAU85359.1
Ensembl_TRS:
ENSDART00000169809
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000139404
RefSeq:
NP_956892.1
|
| Others |
UniRef100:
UniRef100_Q6PGZ7
UniRef90:
UniRef90_Q6PGZ7
UniRef50:
UniRef50_O14896
UniGene:
Dr.81664
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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