| Type | Description |
|---|---|
| Definition | LCK proto-oncogene, Src family tyrosine kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:29:00 | LCK rs10914542-G allele associates with type 1 diabetes in children via T cell hyporesponsiveness. | 31112992 |
| 2020-07-25 12:29:00 | These results show that both the activation and deactivation processes could follow distinct pathways, differentiated by the order by which the A-loop and the C-helix regions rearrange. | 31077013 |
| 2020-06-27 11:30:00 | The ITK SH3 and LCK SH3 domains can both competefor and simultaneously bind to adjacent binding sites on TSAD encompassing aa 242-268. | 31484725 |
| 2019-11-16 10:56:00 | These findings suggest TSLP/p56lck plays an important role in allergic reactions and offers opportunities for the development of novel drugs for the treatment of AR. | 29752758 |
| 2019-11-09 12:01:00 | these results provide strong evidence that mutated and overexpressed Lck is driving acute myeloid leukemia cell, CTV-1, proliferation | 30660961 |
| Type | IDs |
|---|---|
| Synonymous | IMD22, LSK, YT16, p56lck, pp58lck |
| Gene |
UniProtKB-ID:
LCK_HUMAN,
A0A0S2Z3Y4_HUMAN,
Q573B4_HUMAN,
A0A0S2Z3Y8_HUMAN
UniprotKB:
P06239,
A0A0S2Z3Y4,
Q573B4,
A0A0S2Z3Y8
UniParc:
UPI000016A1AE,
UPI0000151F17,
UPI0000169F3B,
UPI0000D6BBD9,
UPI00004F77E3
EMBL:
KU178163,
AF228313,
KU178162,
AL121991,
X05027,
AL109945,
CH471059,
BC013200,
M26692,
X14055,
M21510,
X13529,
M36881,
X04476,
U23852,
U07236,
X06369,
BN000073,
X14054,
AJ865079,
X14053
Ensembl:
ENSG00000182866
KO:
hsa:3932
|
| Nucleutide sequences |
EMBL-CDS:
CAA32211.1,
CAA29667.1,
AAA18225.1,
CAA31884.1,
EAX07546.1,
AAA59502.1,
EAX07543.1,
AAA59501.1,
AAF34794.1,
AAH13200.1,
CAA28165.1,
AAC50287.1,
AAA59503.1,
CAD55807.1,
CAA28691.1,
ALQ33621.1,
CAI23831.1,
ALQ33620.1
Ensembl_TRS:
ENST00000336890,
ENST00000619559,
ENST00000333070,
ENST00000373564
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000477713,
ENSP00000328213,
ENSP00000337825,
ENSP00000362665
RefSeq:
NP_001317397.1,
NP_001036236.1,
NP_005347.3,
XP_011539755.1,
XP_024302815.1,
XP_024302814.1
|
| Others |
UniRef100:
UniRef100_Q573B4,
UniRef100_A0A0S2Z3Y4,
UniRef100_P06239
UniRef90:
UniRef90_P06239,
UniRef90_A0A2K5EMU3,
UniRef90_Q573B4
UniRef50:
UniRef50_P06239
UniGene:
Hs.470627
CCDS:
CCDS359.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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