| Type | Description |
|---|---|
| Definition | alpha-hemolysin |
| Date | Results | Publications |
|---|---|---|
| 2016-12-17 12:13:00 | We now show that ADAM10 is critical for alpha-hemolysin-mediated activation of the NLRP3 inflammasome in human monocytes as siRNA knockdown or chemical blockade of ADAM10-alpha-hemolysin interaction leads to diminished inflammasome activation and cell death by reducing the available ADAM10 on the cell surface. | 27043625 |
| 2015-03-21 11:01:00 | Staphylococcus aureus hemolysin A disrupts cell-matrix adhesions in human airway epithelial cells. | 24918472 |
| 2011-06-04 11:26:00 | Succeeded in preparing crystals of the heptameric form of alpha-hemolysin without any detergent but with 2-methyl-2,4-pentanediol (MPD), and determined its structure. | 21280135 |
| 2010-03-15 12:05:00 | Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells | 19826485 |
| 2010-01-21 00:00:00 | The wide vestibule leading into the alpha-hemolysin pore helps to orient negatively charged synthetic alpha-helical peptides for translocation. | 16866363 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
HLA_STAA8
UniprotKB:
Q2G1X0
UniParc:
UPI00004B5BAF
EMBL:
CP000253
EnsemblGenome:
SAOUHSC_01121
KO:
sao:SAOUHSC_01121
|
| Nucleutide sequences |
EMBL-CDS:
ABD30233.1
EnsemblGenome_TRS:
ABD30233
|
| Protein sequencees |
EnsemblGenome_PRO:
ABD30233
RefSeq:
YP_499665.1
|
| Others |
UniRef100:
UniRef100_Q2G1X0
UniRef90:
UniRef90_P09616
UniRef50:
UniRef50_P09616
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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