| Type | Description |
|---|---|
| Definition | Rho GTPase activating protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-10-28 12:51:00 | identified ARHGAP1, which is a negative regulator of CDC42, as a novel, direct target of miR-130b | 28748534 |
| 2017-08-05 12:47:00 | to complete invasion of the endothelium, staphylococci reorient recycling endocytic vesicles to recruit Cdc42GAP. | 27311480 |
| 2017-07-29 11:56:00 | we identified novel associations in WLS , ARHGAP1 , and 5' of MEF2C ( P- values < 8x10 - 5 ; false discovery rate (FDR) q-values < 0.01) that were much more strongly associated with BMD compared to the GWAS SNPs. | 27616567 |
| 2014-07-19 10:42:00 | study shows that HMHA1 acts as a RhoGAP to regulate GTPase activity, cytoskeletal remodeling and cell spreading, which are crucial functions in normal hematopoietic and cancer cells | 24086303 |
| 2013-12-21 11:08:00 | The interaction of RhoGap protein stabilizes the tetrameric conformation of p53 and enhances its DNA-binding activity, thereby inducing cell-cycle arrest and apoptosis. | 23684608 |
| Type | IDs |
|---|---|
| Synonymous | CDC42GAP, RHOGAP, RHOGAP1, p50rhoGAP |
| Gene |
UniProtKB-ID:
RHG01_HUMAN
UniprotKB:
Q07960
UniParc:
UPI0000040691
EMBL:
U02570,
BC018118,
Z23024,
CH471064
Ensembl:
ENSG00000175220
KO:
hsa:392
|
| Nucleutide sequences |
EMBL-CDS:
AAA16142.1,
EAW67983.1,
CAA80560.1,
AAH18118.1,
EAW67984.1
Ensembl_TRS:
ENST00000311956
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000310491
RefSeq:
XP_011518397.1,
XP_024304288.1,
NP_004299.1
|
| Others |
UniRef100:
UniRef100_Q07960
UniRef90:
UniRef90_Q07960
UniRef50:
UniRef50_Q07960
UniGene:
Hs.138860
CCDS:
CCDS7922.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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