Type | Description |
---|---|
Definition | VHL like |
Date | Results | Publications |
---|---|---|
2020-05-09 13:35:00 | von Hippel-Lindau-like protein (VLP) is conserved in upper mammals and specifically expressed in brain and testis. Structural analysis and molecular dynamics simulations show VLP to be similar to von Hippel-Lindau tumor suppressor protein (pVHL) three-dimensional organization and binding dynamics. Conservation of elements at the protein interfaces suggests VLP to be a functional pVHL homolog possessing multiple functions. | 31485743 |
Type | IDs |
---|---|
Synonymous | VHLP, VLP |
Gene |
UniProtKB-ID:
VHLL_HUMAN
UniprotKB:
Q6RSH7
UniParc:
UPI0000253B18
EMBL:
AY494836,
BC130596,
BC130598
Ensembl:
ENSG00000189030
KO:
hsa:391104
|
Nucleutide sequences |
EMBL-CDS:
AAI30597.1,
AAI30599.1,
AAS48916.1
Ensembl_TRS:
ENST00000339922
|
Protein sequencees |
Ensembl_PRO:
ENSP00000464258
RefSeq:
NP_001004319.1
|
Others |
UniRef100:
UniRef100_Q6RSH7
UniRef90:
UniRef90_Q6RSH7
UniRef50:
UniRef50_Q6RSH7
UniGene:
Hs.532378
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
31485743 |
Insights into the molecular features of the von Hippel-Lindau-like protein. Amino Acids Giovanni Minervini , Federica Quaglia , Francesco Tabaro , Silvio C E Tosatto |
2019-11-01 | - |
25416956 |
A proteome-scale map of the human interactome network. Cell Thomas Rolland , Murat TaÅan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , Amélie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , Jörg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-László Barabási , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal |
2014-11-20 | - |
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
20139978 |
Genome-wide association study of hematological and biochemical traits in a Japanese population. Nat. Genet. Yoichiro Kamatani , Koichi Matsuda , Yukinori Okada , Michiaki Kubo , Naoya Hosono , Yataro Daigo , Yusuke Nakamura , Naoyuki Kamatani |
2010-03-01 |
SH2B3,
TIMM23,
RCL1,
CDK6,
TRIB1,
DENND4A,
LOC102724766,
CITED2,
CDSN,
CETP,
SLC12A7,
HBS1L,
GLMP,
KLHDC7B,
SLC22A12,
APOA5,
AGAP4,
ATP6V1G3,
TSACC,
ZDHHC19,
CSF3,
TMPRSS6,
PSORS1C1,
TYMP,
ALDH2,
MARCH8,
CCDC162P,
FCGRT,
XPO7,
HIC2,
SMG5,
TNFRSF13B,
RPL13A,
ALOX5,
ALPL,
FAM21C,
WDR72,
SAMM50,
USP49,
TRIM58,
GCKR,
GGT1,
ANGPTL3,
GP1BA,
ABO,
GPLD1,
GSDMA,
CEP57L1,
PARVB,
NCAPH2,
HIST1H1T,
HBA1,
HBA2,
HFE,
HK1,
APOA1,
APOA4,
APOC3,
KIT,
VHLL,
LIPC,
LPL,
LRP2,
MRC1,
MSMB,
MYB,
AK3,
HACD3,
PDGFRA,
DPP8,
SLC35E3,
RBM38,
LUC7L,
PRKCE,
SLC2A9,
PSMD3,
NUP107,
RCN3,
IGDCC4,
BAK1,
PTPRC,
RAP1B,
RPS11,
BGLAP,
TMEM236,
TERT,
TFRC,
BYSL,
THPO,
THRB,
CCT3,
UBE2L3,
PAQR6,
NCOA4,
PNPLA3,
VWA9,
CDT1,
SLC14A2,
BRAP
|
14757845 |
Molecular cloning and characterization of the von Hippel-Lindau-like protein. Mol. Cancer Res. Heng Qi , Michelle L Gervais , Wei Li , James A DeCaprio , John R G Challis , Michael Ohh |
2004-01-01 |
Vhl-ps1,
HIF1A,
VHLL
|
12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
10475385 |
Processed pseudogene from the von Hippel-Lindau disease gene is located on human chromosome 1. Diagn. Mol. Pathol. J F Bradley , P G Rothberg |
1999-06-01 | - |
7566098 |
Nature M D Adams , A R Kerlavage , R D Fleischmann , R A Fuldner , C J Bult , N H Lee , E F Kirkness , K G Weinstock , J D Gocayne , O White |
1995-09-28 |
FCGR1CP,
PITPNA-AS1,
RPARP-AS1,
LOC100505920,
PLCB1-IT1,
XXYLT1-AS2,
LOC101926941,
PIK3CD-AS2,
NRG3-AS1,
CDK6,
LOC102724745,
LYPLA1,
LINC01054,
EMG1,
ZBTB18,
LINC01402,
PKD1P6-NPIPP1,
LOC105373352,
PLA2G4C-AS1,
REV3L-IT1,
TUBGCP2,
SERINC3,
KCNQ1OT1,
ADAMTS6,
KLK8,
NXPH3,
SYNPO,
MRPL54,
BORCS7,
TANGO2,
NADK2,
ASB12,
OR51E1,
FAM161B,
VCAN,
ADRA1A,
PPP1R1C,
CABP7,
DNMT3A,
DPP6,
ANO6,
AHR,
ELK4,
CTTN,
TMEM192,
EP300,
FABP1,
VWCE,
KDM1B,
THSD7A,
RAB18,
EPB41L3,
SSBP3,
APOL2,
STH,
EBF3,
LPCAT4,
SHPRH,
SVIP,
DNAJB5,
RWDD3,
RNF167,
ZNF451,
GAPVD1,
FBXO25,
CKAP2,
FOXP1,
SIT1,
UTP20,
GLI3,
CDH19,
MCTS1,
GTF2F1,
CYP2S1,
GUCA2A,
GPR171,
GYPA,
NRBF2,
SH3KBP1,
NUDT2,
HOXC4,
ZBTB8OS,
PWARSN,
PKD1P6,
CXCL10,
IRF2,
PI4KAP2,
KPNA5,
KRTDAP,
VHLL,
ABLIM1,
ARL3,
HOXB-AS3,
CCL3L3,
FAM35BP,
MAP3K4,
METTL1,
MGST1,
OR2A9P
|
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