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3908 LAMA2

3908

LAMA2

laminin subunit alpha 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition laminin subunit alpha 2

研究结论

Date Results Publications
2021-03-28 19:05:00 Mex3a interacts with LAMA2 to promote lung adenocarcinoma metastasis via PI3K/AKT pathway. 32792503
2020-06-27 11:06:00 lm-alpha2 roll in controlling cell cycle exit and survival in the midbrain dopaminergic neuron neuron lineage 31371375
2019-11-02 12:01:00 the data highlight our approach, a modified next-generation sequencing assay, as a robust and sensitive tool to detect LAMA2 variants; the assay identifies 85.7% of breakpoint junctions directly alongside sequence information. 30301903
2019-05-25 10:32:00 Data provide evidence that LAMA2 mutations cause congenital muscular dystrophy (MD). There are severe, non-ambulatory or milder, ambulatory variants, the latter resulting from reduced LAMA2 expression and/or deficient function. In LAMA2 MD, Lm-411 replaces Lm-211; however, Lm-411 lacks the ability to polymerize and bind to receptors. This results in a weakened basement membrane leading to the disease. [Review] 29191403
2019-03-02 12:25:00 we identified LAMA2 as the coreceptor for staphylococcal superantigens 29335257

名称对应

Type IDs
Synonymous LAMM, MDC1A
Gene
UniProtKB-ID: LAMA2_HUMAN, Q59H37_HUMAN
UniprotKB: P24043, Q59H37
UniParc: UPI00003673E0, UPI00004F6AD6
EMBL: AL583853, U66770, U66788, AL669984, U66795, U66743, AL590613, U66780, U66765, U66782, U66746, U66791, U66753, U66771, U66784, U66766, U66781, U66776, U66789, AL356124, U66754, U66761, U66763, AL445439, U66734, M59832, U66751, U66755, U66747, U66774, U66773, U66756, U66735, U66790, U66778, U66733, U66759, U66787, U66777, AL513527, U66745, U66738, U66783, U66739, U66749, AL589927, U66750, U66786, U66768, U66741, U66794, U66757, U66760, U66785, U66758, U66736, U66752, Z26653, U66796, U66775, U66740, U66779, U66769, U66762, U66792, AB208922, U66748, U66793, U66772, U66737, U66742, U66764
Ensembl: ENSG00000196569
KO: hsa:3908
Nucleutide sequences
EMBL-CDS: CAH70771.1, CAA81394.1, AAB18388.1, CAI22470.1, AAA63215.1, CAI16682.1, CAH72952.1, CAI15185.1, CAH70492.1, BAD92159.1
Ensembl_TRS: ENST00000421865
Protein sequencees
Ensembl_PRO: ENSP00000400365
RefSeq: XP_016866340.1, NP_000417.3, NP_001073291.2, XP_005267039.1, XP_005267038.1, XP_011534122.1, XP_016866342.1, XP_016866341.1
Others
UniRef100: UniRef100_Q59H37, UniRef100_P24043
UniRef90: UniRef90_Q59H37, UniRef90_P24043
UniRef50: UniRef50_P24043
UniGene: Hs.200841
CCDS: CCDS5138.1

全选

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研究热度

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