| Type | Description |
|---|---|
| Definition | Peptidoglycan recognition protein LF |
| Date | Results | Publications |
|---|---|---|
| 2017-05-27 11:31:00 | Negative regulation of NF-kappaB/IMD pathway by PGRP-LF is crucial to ensure proper induction of apoptosis and consequently normal fly development. | 28085885 |
| 2011-08-06 10:37:00 | Data show that the Drosophila peptidoglycan-recognition protein LF interacts with peptidoglycan-recognition protein LC to downregulate the Imd pathway. | 21372849 |
| 2010-01-21 00:00:00 | By genetically interacting with PGRP-LC, PGRP-LF prevents constitutive activation of both the JNK and the immune deficiency pathways in the absence of infection. | 18474356 |
| 2010-01-21 00:00:00 | membrane bound and has its two PGRP domains, z and w, localized outside the cell | 17967349 |
| Type | IDs |
|---|---|
| Synonymous | CG4437, Dmel\CG4437, PGRP-like, PGRPLF, anon-WO0118547.581, pgrp-lf |
| Gene |
UniProtKB-ID:
PGPLF_DROME
UniprotKB:
Q8SXQ7
UniParc:
UPI0000007362
EMBL:
AE014296,
AY084190
EnsemblGenome:
FBgn0035977
KO:
dme:Dmel_CG4437
|
| Nucleutide sequences |
EMBL-CDS:
AAL89928.1,
AAF50301.2
Gene_ORFName:
CG4437
EnsemblGenome_TRS:
FBtr0076439
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0076167
RefSeq:
NP_648299.3
|
| Others |
UniRef100:
UniRef100_Q8SXQ7
UniRef90:
UniRef90_Q8SXQ7
UniRef50:
UniRef50_Q8SXQ7
UniGene:
Dm.20049
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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