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39063 PGRP-LC

39063

PGRP-LC

Peptidoglycan recognition protein LC

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Peptidoglycan recognition protein LC

研究结论

Date Results Publications
2017-12-02 12:15:00 cleaning behavior can be triggered through recognition of DAP-type PGN by its receptor PGRP-LC. 29121087
2017-11-11 12:33:00 Protofibrils of peptidoglycan receptors PGRP-LC and PGRP-LE seed immune deficiency protein (Imd) amyloid polymerization via Imd RIP homotypic interaction motif (RHIM), and the formation of functional Imd amyloid fibril is required for NF-kappaB signaling. 29045898
2017-06-03 12:20:00 this study identifies a novel version of the peptidoglycan receptor PGRP-LC and demonstrate that it tunes immune responses to live (threatening) or dead (harmless) bacteria 27548432
2016-04-30 10:22:00 PGRP-LC immune receptor regulates trans-synaptic signaling, a novel activity for innate immune signaling. 26687223
2015-08-15 10:06:00 Silencing TM9SF4 prevents plasma membrane localization of PGRP-LC, whereas silencing TM9SF2 does not, which may account for the non-redundant role of TM9SF4 in phagocytosis of Gram-negative bacteria. 25139117

名称对应

Type IDs
Synonymous (PGRP)-LC, CG4432, Dm PGRP-LC, Dmel\CG4432, PGRP-LCa, PGRP-LCx, PGRPLC, Pgrp-LC, ird7, pgrp lc, pgrp-lc, tot
Gene
UniProtKB-ID: PGPLC_DROME, M9NDN2_DROME, E1JI89_DROME, A0A0S0WMR4_DROME, E1JI87_DROME, E1JI88_DROME
UniprotKB: Q9GNK5, M9NDN2, E1JI89, A0A0S0WMR4, E1JI87, E1JI88
UniParc: UPI0001B78FFE, UPI0004F13DF6, UPI0000376AB5, UPI0000083BFE, UPI0001C000AF, UPI000007EF43
EMBL: AY327466, AF207539, AF500096, AE014296, AY119048, BT025958
EnsemblGenome: FBgn0035976
KO: dme:Dmel_CG4432
Nucleutide sequences
EMBL-CDS: AAQ16306.1, AAF50302.3, AAG23733.1, AAM18530.1, ABG02202.1, AAM50908.1, AAS65052.1, AAN11957.1, AFH04364.1, ACZ94668.1, ALI30469.1, ACZ94669.1, ACZ94667.1
Gene_ORFName: CG4432, CG4432, Dmel_CG4432, CG4432, Dmel_CG4432, CG4432, Dmel_CG4432, CG4432, Dmel_CG4432, CG4432, Dmel_CG4432
EnsemblGenome_TRS: FBtr0308349, FBtr0089490, FBtr0300290, FBtr0089491, FBtr0308349, FBtr0089491, FBtr0300291, FBtr0346814, FBtr0301773, FBtr0300290, FBtr0089490
Protein sequencees
EnsemblGenome_PRO: FBpp0088491, FBpp0289518, FBpp0088492, FBpp0300668, FBpp0088492, FBpp0300668, FBpp0289519, FBpp0312389, FBpp0290987, FBpp0088491, FBpp0289518
RefSeq: NP_001163397.1, NP_001246693.1, NP_001350860.1, NP_648298.1, NP_729468.2, NP_001350859.1, NP_001163396.1, NP_996030.1, NP_001303367.1, NP_001163398.1
Others
UniRef100: UniRef100_A0A0S0WMR4, UniRef100_E1JI87, UniRef100_E1JI88, UniRef100_Q9GNK5, UniRef100_E1JI89
UniRef90: UniRef90_E1JI87, UniRef90_E1JI88, UniRef90_E1JI89, UniRef90_Q9GNK5
UniRef50: UniRef50_Q9GNK5, UniRef50_E1JI89, UniRef50_E1JI87
UniGene: Dm.1437

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