SERPINA2 - serpin family A member 2 (gene/pseudogene)-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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390502 SERPINA2

基因描述

Type	Description
Definition	serpin family A member 2 (gene/pseudogene)

研究结论

Date	Results	Publications
2014-02-08 12:35:00	Specific features of SERPINA2 include the absence of insoluble aggregates and the insignificant response to cell stress, suggesting that it is a non-polymerogenic protein with divergent activity of SERPINA1.	23826168
2010-12-05 22:08:00	Observational study of gene-disease association. (HuGE Navigator)	11161981
2010-01-21 00:00:00	Study found that a common haplotype in Africa had a 2-kb deletion in the SERPINA2 gene is associated with remarkable long-range homozygozity as if it was quickly driven to high frequency by natural selection acting on an advantageous variant.	17135331
2009-12-02 21:41:00	Clinical trial and genome-wide association study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)	18519826

名称对应

Type	IDs
Synonymous	ARGS, ATR, PIL, SERPINA2P, psiATR
Gene	UniProtKB-ID: A0A0G2JPK4_HUMAN, S4UD68_HUMAN UniprotKB: A0A0G2JPK4, S4UD68 UniParc: UPI00035843C6, UPI0003ED8B83 EMBL: JX680599, AC235087 Ensembl: ENSG00000274821 KO: hsa:390502
Nucleutide sequences	EMBL-CDS: AGI62067.1 Ensembl_TRS: ENST00000616052, ENST00000613989
Protein sequencees	Ensembl_PRO: ENSP00000483813, ENSP00000477957 RefSeq: NP_006211.2
Others	UniRef100: UniRef100_A0A0G2JPK4, UniRef100_S4UD68 UniRef90: UniRef90_G3QXZ4 UniRef50: UniRef50_P20848

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
23826168	SERPINA2 is a novel gene with a divergent function from SERPINA1. PLoS ONE PatrÃcia Isabel Marques , ZÃ©lia Ferreira , Manuella Martins , Joana Figueiredo , Diana Isabel Silva , PatrÃcia Castro , Ramiro Morales-Hojas , Joana SimÃµes-Correia , Susana Seixas	2013-01-01	PDIA3, SERPINA2, SERPINA1, CANX
24172014	Update of the human and mouse SERPIN gene superfamily. Hum. Genomics Claire Heit , Brian C Jackson , Monica McAndrews , Mathew W Wright , David C Thompson , Gary A Silverman , Daniel W Nebert , Vasilis Vasiliou	2013-01-01	Agt, Serpinb7, Serpinc1, Serping1, Serpina6, Serpind1, Serpina3c, Serpine1, Serpinb2, Serpinf2, Serpinb3a, Serpinf1, Serpina1a, Serpina1b, Serpina1c, Serpina1d, Serpina1e, Serpinb9b, Serpinb9c, Serpinb6b, Serpinb9f, Serpinb9e, Serpini1, Serpina3k, Serpina3g, Serpina3n, Serpina3m, Serpinb6a, Serpine2, Serpinb9, Serpinb5, Serpinb8, Serpinb9d, Serpina10, Serpina3f, Serpina3j, Serpinb6d, Serpinb13, Serpinb10, Serpina5, Serpina3b, Serpinb1b, Serpinb1-ps1, Serpine3, Serpina4-ps1, Serpina7, Serpina11, Serpinb1c, Serpinb3c, Serpinb3b, Serpinb3d, Serpina3d-ps, Serpinb6e, Serpina3h, Serpina3e-ps, Serpina3i, Serpina3l-ps, Serpinb1a, Serpinb11, Serpini2, Serpina12, Serpina1f, Serpinb12, Serpina9, Serpina3a, Serpinb9g, Serpinb6c, SERPINA7P1, SERPINA15P, SERPINE4P, SERPINB8P1, SERPINA3, SERPINA12, SERPINH1P1, AGT, SERPINB1, SERPINB9P1, SERPINA11, SERPIND1, SERPINA9, SERPINA13P, SERPINA2, SERPINC1, SERPINE1, SERPINB2, SERPINA5, SERPINA10, SERPINF1, SERPINA1, SERPINA4, SERPINB5, SERPINB6, SERPINE2, SERPINB8, SERPINB9, SERPINB10, SERPINI1, SERPINB13, SERPINI2
21988832	Toward an understanding of the protein interaction network of the human liver. Mol. Syst. Biol. Jian Wang , Keke Huo , Lixin Ma , Liujun Tang , Dong Li , Xiaobi Huang , Yanzhi Yuan , Chunhua Li , Wei Wang , Wei Guan , Hui Chen , Chaozhi Jin , Juncheng Wei , Wanqiao Zhang , Yongsheng Yang , Qiongming Liu , Ying Zhou , Cuili Zhang , Zhihao Wu , Wangxiang Xu , Ying Zhang , Tao Liu , Donghui Yu , Yaping Zhang , Liang Chen , Dewu Zhu , Xing Zhong , Lixin Kang , Xiang Gan , Xiaolan Yu , Qi Ma , Jing Yan , Li Zhou , Zhongyang Liu , Yunping Zhu , Tao Zhou , Fuchu He , Xiaoming Yang	2011-10-11	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
18519826	Molecular genetics of successful smoking cessation: convergent genome-wide association study results. Arch. Gen. Psychiatry George R Uhl , Qing-Rong Liu , Tomas Drgon , Catherine Johnson , Donna Walther , Jed E Rose , Sean P David , Ray Niaura , Caryn Lerman	2008-06-01	ATP9A, CDH13, ATP8A1, TACC2, NRG3, ADCY2, PTPRT, AKAP13, CHN2, SORCS1, OLFM3, BTBD16, CD109, CCBE1, CTNNA2, PEBP4, DAB1, TMTC2, DAPK1, TDRD5, GLIS3, DPP6, DSCAM, ERG, ADGRF5, FDX1, ALDH3A2, FGF12, ITGA11, TNIK, ZNF423, KAZN, BCL2L13, C4orf22, ST6GALNAC3, ERC2, LAMA1, GRIK1, GRIK2, LUZP2, ITPR2, CERKL, KCNK2, KCNN3, SERPINA2, FLJ42220, UNC13C, GALNTL6, ASTN1, NELL1, CCDC73, PARK2, PAX9, SERPINA1, PKP1, NECAB2, RBFOX1, BNC2, ARHGEF38, PPP2R2B, P3H2, CACNA2D3, PBK, PRKG1, SALL4, DSCAML1, MTUS1, WDFY4, PTPN2, PTPRD, RARB, REN, BIK, NPAS3, CLSTN2, CSMD1, ST3GAL1, SLC1A2, PCDH15, TMEM108, SNAP25, SOX5, TEK, TRIO, USH2A, NPHS2, CACNB2, MOB3B, NEK11, THSD4, KCNIP4, ADAM12, LYZL1, SUPT3H, MYO18B, SEMA5A, LARGE, MAGI1, NRXN3
17135331	Sequence diversity at the proximal 14q32.1 SERPIN subcluster: evidence for natural selection favoring the pseudogenization of SERPINA2. Mol. Biol. Evol. Susana Seixas , Gianpaolo Suriano , Filipa Carvalho , Raquel Seruca , Jorge Rocha , Anna Di Rienzo	2007-02-01	SERPINA2
15769666	Organization and expression of the human serpin gene cluster at 14q32.1. Front. Biosci. Mark D Marsden , R E K Fournier	2005-05-01	-
15014966	Sequence organization and matrix attachment regions of the human serine protease inhibitor gene cluster at 14q32.1. Mamm. Genome Stephanie J Namciu , Richard D Friedman , Mark D Marsden , Lourdes M Sarausad , Christine L Jasoni , R E K Fournier	2004-03-01	SERPINA3, IFI27L1, GSC, RPSAP4, SERPINA12, LINC00521, SERPINA11, SERPINA9, IFI27, SERPINA13P, SERPINA2, SERPINA5, SERPINA10, ASB2, SERPINA1, SERPINA4, DDX24, PPP4R4, OTUB2, IFI27L2, SERPINA6
12878320	Mechanisms of alpha1-antitrypsin inhibition of cellular serine proteases and HIV-1 protease that are essential for HIV-1 morphogenesis. Biochim. Biophys. Acta Pierre Cordelier , David S Strayer	2003-07-30	-
12621451	HIV-1 proprotein processing as a target for gene therapy. Gene Ther. P Cordelier , M A Zern , D S Strayer	2003-03-01	gag, env, SERPINA2, SERPINA1

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