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3903 LAIR1

3903

LAIR1

leukocyte associated immunoglobulin like receptor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition leukocyte associated immunoglobulin like receptor 1

研究结论

Date Results Publications
2021-04-17 13:11:00 LAIR-1 overexpression inhibits epithelial-mesenchymal transition in osteosarcoma via GLUT1-related energy metabolism. 32563267
2020-10-24 14:09:00 Leukocyte-associated immunoglobulin-like receptor 1 inhibits T-cell signaling by decreasing protein phosphorylation in the T-cell signaling pathway. 31932281
2020-10-03 12:59:00 Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8(+) T cell exhaustion. 32908154
2020-09-12 10:29:00 LAIR1 was significantly upregulated in clinical specimens of human renal cell carcinoma (RCC) tumor tissues compared to that noted in adjacent noncancerous renal tissues. RCC patients with high LAIR1 mRNA expression showed poor progressionfree survival compared to those with low LAIR1 expression. 30483814
2020-08-13 18:51:00 Signal inhibitory receptor on leukocytes (SIRL)-1 and leukocyte- associated immunoglobulin-like receptor (LAIR)-1 regulate neutrophil function in infants. 31843567

名称对应

Type IDs
Synonymous CD305, LAIR-1
Gene
UniProtKB-ID: LAIR1_HUMAN, A8MZ84_HUMAN, D3YTC8_HUMAN
UniprotKB: Q6GTX8, A8MZ84, D3YTC8
UniParc: UPI0000118A9C, UPI000011A058, UPI000387B290, UPI0000117CF1, UPI000387DABA, UPI0000118A9D
EMBL: AC245884, AF013249, BC027899, CR542051, AF109683, AF251510, AF251509
Ensembl: ENSG00000278154, ENSG00000276163, ENSG00000167613, ENSG00000276053, ENSG00000274110
KO: hsa:3903
Nucleutide sequences
EMBL-CDS: CAG46848.1, AAF17107.1, AAF71274.2, AAB69324.1, AAH27899.1, AAF71275.2
Ensembl_TRS: ENST00000619817, ENST00000614946, ENST00000391742, ENST00000620726, ENST00000614937, ENST00000620077, ENST00000474878, ENST00000616612, ENST00000610549, ENST00000620357, ENST00000619717, ENST00000622097, ENST00000348231, ENST00000618434, ENST00000391743, ENST00000434277
Protein sequencees
Ensembl_PRO: ENSP00000418998, ENSP00000478405, ENSP00000479649, ENSP00000480619, ENSP00000301193, ENSP00000479682, ENSP00000478853, ENSP00000480659, ENSP00000482922, ENSP00000481204, ENSP00000479006, ENSP00000479133, ENSP00000375622, ENSP00000479707, ENSP00000375623, ENSP00000391003
RefSeq: NP_001275956.2, NP_001275955.2, NP_001275952.2, XP_016882292.1, NP_068352.2, NP_001275954.2, NP_002278.2
Others
UniRef100: UniRef100_Q6GTX8, UniRef100_A8MZ84, UniRef100_D3YTC8
UniRef90: UniRef90_Q6GTX8
UniRef50: UniRef50_Q6GTX8
UniGene: Hs.572535
CCDS: CCDS74448.1, CCDS12892.1, CCDS12891.1

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