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390 RND3

390

RND3

Rho family GTPase 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition Rho family GTPase 3

研究结论

Date Results Publications
2020-02-22 10:34:00 uncovered a novel differential expression of adipose RND3 in obesity and insulin resistance, which may at least partly depend on a causal effect of RND3 on adipocyte lipolysis. 31672447
2019-12-07 11:24:00 The study uncovers RhoE as a new fine-tuning factor modulating myocardial infarction-induced inflammation and promoting injured heart recovery. 30586715
2019-12-07 11:11:00 In pre-eclampsia, increased miRNA-182-5p expression could inhibit the migratory and invasive ability of trophoblast cells through targeted degradation of RND3 protein. 30402829
2019-10-26 12:05:00 RND3 bound p65 and promoted the ubiquitination of p65 protein, leading to reduced expression of p65 protein and inhibition of the NF-kappaB signalling pathway and its downstream target genes IL-8 and BCL-2 to promote apoptosis in GBM cells. 31332862
2019-09-21 12:14:00 Rnd3 is a MKL1-SRF target that plays a key role in the feedback loop described between the MKL1-SRF pathway and the organization of the actin cytoskeleton 29940177

名称对应

Type IDs
Synonymous ARHE, Rho8, RhoE, memB
Gene
UniProtKB-ID: RND3_HUMAN, B2R838_HUMAN
UniprotKB: P61587, B2R838
UniParc: UPI000175056C, UPI0000003FE9
EMBL: CH471058, BT006769, AF498969, BC012513, X97758, AK313224, X95282, S82240
Ensembl: ENSG00000115963
KO: hsa:390
Nucleutide sequences
EMBL-CDS: CAA64603.1, EAX11524.1, AAP35415.1, EAX11526.1, AAH12513.1, AAB47133.1, CAA66352.1, AAM21116.1, BAG36035.1
Ensembl_TRS: ENST00000375734, ENST00000263895
Protein sequencees
Ensembl_PRO: ENSP00000263895, ENSP00000364886
RefSeq: NP_005159.1, NP_001241667.1
Others
UniRef100: UniRef100_P61587, UniRef100_B2R838
UniRef90: UniRef90_P61587
UniRef50: UniRef50_P61587
UniGene: Hs.6838, Hs.713765
CCDS: CCDS2190.1

全选

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