| Type | Description |
|---|---|
| Definition | AF4/FMR2 family member 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-01-19 11:40:00 | AFF3 was overexpressed in tamoxifen-resistant tumors. AFF3 overexpression in breast cancer cells resulted in tamoxifen resistance, whereas RNA interference-mediated gene knockdown reversed this phenotype. | 30326937 |
| 2018-02-10 10:03:00 | Data identified AFF3 as an interactive protein with beclin1 and suggest that AFF3 is probably a key regulator of Beclin-1. | 28401970 |
| 2015-09-26 21:40:00 | Both the AFF3 and NTM triglyceride associations were replicated among Multi-ethnic Study of Atherosclerosis study participants (P = 1.00 x 10(-7) and 8.00 x 10(-5), respectively). | 25819087 |
| 2014-11-29 12:09:00 | FRA2A-expressing individuals have mosaic expansions of the AFF3 CGG repeat. | 24763282 |
| 2013-02-02 11:58:00 | Significant evidence for association of AFF3 rs10865035 with systgemic lupus erythmatgosus was detected. | 22983539 |
| Type | IDs |
|---|---|
| Synonymous | LAF4, MLLT2-like |
| Gene |
UniProtKB-ID:
AFF3_HUMAN,
Q8NAP7_HUMAN
UniprotKB:
P51826,
Q8NAP7
UniParc:
UPI0000545268,
UPI0000545269,
UPI00000720BF
EMBL:
AC073118,
BC144266,
BC036895,
AB209634,
AK092327,
U34360,
AC018690,
BC136579,
AC010736,
AC092667,
CH471127
Ensembl:
ENSG00000144218
KO:
hsa:3899
|
| Nucleutide sequences |
EMBL-CDS:
AAI44267.1,
AAY14792.1,
EAX01857.1,
BAD92871.1,
EAX01858.1,
AAY24278.1,
AAA98763.1,
EAX01859.1,
AAI36580.1,
EAX01855.1,
AAY24315.1,
AAY24187.1,
EAX01854.1,
EAX01856.1,
AAH36895.1,
BAC03864.1
Ensembl_TRS:
ENST00000409579,
ENST00000409236,
ENST00000672756,
ENST00000317233
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000386834,
ENSP00000317421,
ENSP00000387207,
ENSP00000500419
RefSeq:
XP_011509473.2,
XP_016859576.1,
NP_001373064.1,
XP_005264002.1,
XP_011509476.1,
XP_016859575.1,
NP_001020279.1,
XP_011509480.1,
XP_011509471.2,
XP_005264000.2,
XP_016859574.1,
XP_011509481.1,
XP_011509477.1,
XP_011509478.1,
XP_011509472.1,
NP_002276.2,
XP_024308651.1,
XP_011509475.1,
XP_011509479.1
|
| Others |
UniRef100:
UniRef100_P51826,
UniRef100_Q8NAP7
UniRef90:
UniRef90_Q8NAP7,
UniRef90_P51826
UniRef50:
UniRef50_P51826,
UniRef50_K7E3G8
UniGene:
Hs.444414
CCDS:
CCDS33258.1,
CCDS42723.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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