| Type | Description |
|---|---|
| Definition | ubiquitin specific peptidase 27 X-linked |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 11:58:00 | The USP27X is a novel regulator of theCyclic GMP-AMP synthase (cGAS)-STING cytosolic DNA sensing pathway. | 31534008 |
| 2020-05-09 14:06:00 | these studies uncover a novel negative regulatory role of USP27X in targeting RIG-I to balance innate immune responses. | 32027733 |
| 2019-10-26 11:22:00 | High USP27X expression is associated with Chemoresistance in breast cancer by Stabilization of Snail1. | 30341066 |
| 2019-03-02 11:37:00 | Data found that USP27 promotes Cyclin E stability by negatively regulating its ubiquitination and regulates its abundance to accelerate cell cycle progression, cell proliferation, and hepatocellular carcinoma cell growth as well. | 29497124 |
| 2017-08-19 11:20:00 | Usp27x can trigger via its proteolytic activity the deubiquitination of Bim and enhance its levels, counteracting the anti-apoptotic effects of ERK activity, and therefore acts as a tumour suppressor. | 27013495 |
| Type | IDs |
|---|---|
| Synonymous | MRX105, USP22L, USP27 |
| Gene |
UniProtKB-ID:
UBP27_HUMAN
UniprotKB:
A6NNY8
UniParc:
UPI0000EE7A8D
EMBL:
AF238380,
DR004246
Ensembl:
ENSG00000273820
KO:
hsa:389856
|
| Nucleutide sequences |
Ensembl_TRS:
ENST00000621775
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000483631
RefSeq:
NP_001138545.1
|
| Others |
UniRef100:
UniRef100_A6NNY8
UniRef90:
UniRef90_A6NNY8
UniRef50:
UniRef50_A6NNY8
UniGene:
Hs.143587
CCDS:
CCDS65260.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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