| Type | Description |
|---|---|
| Definition | proteasome assembly chaperone 4 |
| Date | Results | Publications |
|---|---|---|
| 2017-09-02 10:14:00 | PSMG4 and NLRP5 appear of particular interest as they were found to be associated with more than one clinical phenotype and are implicated in biological processes considered relevant to the pathophysiology of MS. Also, PSMG4 p.W99R and NLRP5 p.R761L were found to correlate with an earlier age of MS clinical onset. Our data suggests PSMG4 and NLPR5 as potential targets for the development of modifying therapies for MS. | 28501589 |
| 2017-07-22 13:12:00 | a crystal structure of human PAC4 at 1.90-A resolution. Crystallographic data identify a hydrophobic surface that is surrounded by charged residues. The hydrophobic surface is complementary to that of its binding partner, PAC3. | 28263418 |
| Type | IDs |
|---|---|
| Synonymous | C6orf86, PAC4, bA506K6.2 |
| Gene |
UniProtKB-ID:
PSMG4_HUMAN,
D6RB92_HUMAN
UniprotKB:
Q5JS54,
D6RB92
UniParc:
UPI000020E429,
UPI00001D810B,
UPI000020E424,
UPI000020E42B
EMBL:
AL445309,
CD173424,
CH471087
Ensembl:
ENSG00000180822
KO:
hsa:389362
|
| Nucleutide sequences |
EMBL-CDS:
EAW55130.1
Ensembl_TRS:
ENST00000438998,
ENST00000473000,
ENST00000419065,
ENST00000324987
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000413353,
ENSP00000418241,
ENSP00000392353,
ENSP00000424330
RefSeq:
NP_001129222.1,
XP_011512895.1,
NP_001122063.1,
XP_011512893.1,
NP_001122064.1,
XP_011512897.1,
XP_011512896.1
|
| Others |
UniRef100:
UniRef100_Q5JS54,
UniRef100_D6RB92
UniRef90:
UniRef90_Q5JS54,
UniRef90_D6RB92
UniRef50:
UniRef50_Q5JS54,
UniRef50_D6RB92
UniGene:
Hs.207069,
Hs.731726
CCDS:
CCDS47361.1,
CCDS47360.1,
CCDS47362.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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