| Type | Description |
|---|---|
| Definition | solute carrier family 9 member A4 |
| Date | Results | Publications |
|---|---|---|
| 2012-03-10 11:43:00 | Data demonstrate functional NHE4 activity in the rat and human colon and suggest that this exchanger is capable of modulating intracellular pH over a wide pH spectrum and may play an important role in maintaining cellular pH homeostasis. | 22049213 |
| 2010-01-21 00:00:00 | T84 human colon cells contain three isoforms of the Na+/H+ exchanger, NHE1, NHE2, and NHE4, but not the Cl-dependent NHE | 17943310 |
| Type | IDs |
|---|---|
| Synonymous | NHE4 |
| Gene |
UniProtKB-ID:
SL9A4_HUMAN
UniprotKB:
Q6AI14
UniParc:
UPI000047F996
EMBL:
CR627411,
AC007278,
AL833048
Ensembl:
ENSG00000180251
KO:
hsa:389015
|
| Nucleutide sequences |
EMBL-CDS:
CAH10500.1,
CAH10600.1
Ensembl_TRS:
ENST00000295269
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000295269
RefSeq:
NP_001011552.2,
XP_011509460.1
|
| Others |
UniRef100:
UniRef100_Q6AI14
UniRef90:
UniRef90_Q6AI14
UniRef50:
UniRef50_Q8BUE1
UniGene:
Hs.447686
CCDS:
CCDS33264.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 24874739 |
Cell Death Dis M Hashimoto , H Nasser , T Chihara , S Suzu |
2014-01-01 |
Map3k7,
nef,
SLC9A6,
CHUK,
MAPK14,
SLC9A8,
SLC9A9,
IKBKB,
SLC9A4,
MAPK1,
MAPK3,
MAPK8,
SLC9A1,
SLC9A2,
SLC9A3,
SLC9A5,
MAP3K7,
SLC9A7,
IL32,
CD163
|
| 23999434 |
Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling. J. Clin. Invest. Jennifer E Ho , Wei-Yu Chen , Ming-Huei Chen , Martin G Larson , Elizabeth L McCabe , Susan Cheng , Anahita Ghorbani , Erin Coglianese , Valur Emilsson , Andrew D Johnson , Stefan Walter , Nora Franceschini , Christopher J O'Donnell , CARDIoGRAM Consortium , CHARGE Inflammation Working Group , Abbas Dehghan , Chen Lu , Daniel Levy , Christopher Newton-Cheh , CHARGE Heart Failure Working Group , Honghuang Lin , Janine F Felix , Eric R Schreiter , Ramachandran S Vasan , James L Januzzi , Richard T Lee , Thomas J Wang |
2013-10-01 |
APCDD1,
DENND1B,
IL1R1,
SLC9A4,
PKN2,
ST2,
IL18RAP,
IL1RL2,
IL33,
IL1RL1
|
| 22049213 |
Functional role of NHE4 as a pH regulator in rat and human colonic crypts. Am J Physiol Cell Physiol Elizabeth A Arena , Walter E Longo , Kurt E Roberts , Peter Geibel , Jama Nateqi , Michael Brandstetter , John P Geibel |
2012-01-15 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21738478 |
PLoS Genet. Yukinori Okada , Tomomitsu Hirota , Yoichiro Kamatani , Atsushi Takahashi , Hiroko Ohmiya , Natsuhiko Kumasaka , Koichiro Higasa , Yumi Yamaguchi-Kabata , Naoya Hosono , Michael A Nalls , Ming Huei Chen , Frank J A van Rooij , Albert V Smith , Toshiko Tanaka , David J Couper , Neil A Zakai , Luigi Ferrucci , Dan L Longo , Dena G Hernandez , Jacqueline C M Witteman , Tamara B Harris , Christopher J O'Donnell , Santhi K Ganesh , Koichi Matsuda , Tatsuhiko Tsunoda , Toshihiro Tanaka , Michiaki Kubo , Yusuke Nakamura , Mayumi Tamari , Kazuhiko Yamamoto , Naoyuki Kamatani |
2011-06-01 |
NAALAD2,
LOC101927844,
CDK6,
HBS1L,
CSF3,
ERG,
GATA2,
STXBP6,
CXCL2,
HLA-E,
ITGA4,
SLC9A4,
MYB,
ACOXL,
GSDMC,
PSMD3,
BMP7,
TAS1R1,
SLC45A3,
LMO4
|
| 18311140 |
Newly identified genetic risk variants for celiac disease related to the immune response. Nat. Genet. Karen A Hunt , Alexandra Zhernakova , Graham Turner , Graham A R Heap , Lude Franke , Marcel Bruinenberg , Jihane Romanos , Lotte C Dinesen , Anthony W Ryan , Davinder Panesar , Rhian Gwilliam , Fumihiko Takeuchi , William M McLaren , Geoffrey K T Holmes , Peter D Howdle , Julian R F Walters , David S Sanders , Raymond J Playford , Gosia Trynka , Chris J J Mulder , M Luisa Mearin , Wieke H M Verbeek , Valerie Trimble , Fiona M Stevens , Colm O'Morain , Nicholas P Kennedy , Dermot Kelleher , Daniel J Pennington , David P Strachan , Wendy L McArdle , Charles A Mein , Martin C Wapenaar , Panos Deloukas , Ralph McGinnis , Ross McManus , Cisca Wijmenga , David A van Heel |
2008-04-01 | - |
| 17943310 |
NHE1, NHE2, and NHE4 contribute to regulation of cell pH in T84 colon cancer cells. Pflugers Arch Ana Rosa Beltrán , Marco Antonio RamÃrez , Luciene R Carraro-Lacroix , Yumi Hiraki , Nancy Amaral Rebouças , Gerhard Malnic |
2008-02-01 | - |
| 16344560 |
Genome Res. Kouichi Kimura , Ai Wakamatsu , Yutaka Suzuki , Toshio Ota , Tetsuo Nishikawa , Riu Yamashita , Jun-ichi Yamamoto , Mitsuo Sekine , Katsuki Tsuritani , Hiroyuki Wakaguri , Shizuko Ishii , Tomoyasu Sugiyama , Kaoru Saito , Yuko Isono , Ryotaro Irie , Norihiro Kushida , Takahiro Yoneyama , Rie Otsuka , Katsuhiro Kanda , Takahide Yokoi , Hiroshi Kondo , Masako Wagatsuma , Katsuji Murakawa , Shinichi Ishida , Tadashi Ishibashi , Asako Takahashi-Fujii , Tomoo Tanase , Keiichi Nagai , Hisashi Kikuchi , Kenta Nakai , Takao Isogai , Sumio Sugano |
2006-01-01 |
Nefm,
MED6,
CDH2,
PDZK1P1,
DDTL,
ABI1,
GNPDA1,
GTF2IP4,
ZSCAN30,
SRA1,
TMEM170B,
HOTAIR,
FAM86JP,
LOC100126784,
C8orf88,
LOC100128006,
RAB28P5,
MYHAS,
CDC42P3,
LOC100128979,
LOC100128993,
KTN1-AS1,
LOC100129083,
LOC100129204,
TOPORS-AS1,
LINC00484,
ZNF37BP,
FAM47E,
MRVI1-AS1,
ZNF737,
LOC100130075,
MAPT-IT1,
MIR124-2HG,
LINC00861,
LOC100130238,
LOC100130357,
PARD6G-AS1,
LOC100130547,
NFYC-AS1,
EFCAB10,
LOC100130798,
SBK3,
LOC100130849,
LOC100130872,
LOC100130880,
LOC100130987,
LOC100131047,
LINC01135,
CKMT2-AS1,
ZBTB20-AS1,
WDR86-AS1,
CCDC183-AS1,
SNAP25-AS1,
NEMP2,
ZNF503-AS2,
MIR181A1HG,
DBIL5P,
HDAC6,
MZF1-AS1,
ARMCX4,
LINC00271,
ZNF717,
LOC100132057,
LOC100132111,
CALML3-AS1,
NDUFA6-AS1,
FRG1HP,
FCGR1CP,
GXYLT1P3,
GOLGA8F,
DCAF13P3,
IPO5P1,
MSC-AS1,
SMIM9,
FAM66A,
CD24,
UXT-AS1,
JHDM1D-AS1,
UBE2Q2P2,
TEN1,
JMJD7,
PLA2G4B,
LINC00930,
PDCD6IP,
HECTD2-AS1,
ZFHX4-AS1,
FAR2P2,
LOC100233156,
PCED1B-AS1,
PIGK,
LOC100270746,
LOC100270804,
LINC00940,
ERVV-2,
MEF2B,
ZNRF2P2,
NFE2L3P2,
LINC00894,
BCDIN3D-AS1
|
| 12576672 |
Biol. Pharm. Bull. Hiroki Inoue , Yutaka Nakamura , Mana Nagita , Tomoyo Takai , Miho Masuda , Norihiro Nakamura , Hiroshi Kanazawa |
2003-02-01 | - |
| 8199403 |
Chromosomal assignment of four genes encoding Na/H exchanger isoforms in human and rat. Mamm. Genome C Szpirer , J Szpirer , M Rivière , G Levan , J Orlowski |
1994-03-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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