| Type | Description |
|---|---|
| Definition | major facilitator superfamily domain containing 2B |
| Date | Results | Publications |
|---|---|---|
| 2019-10-12 11:08:00 | Using microarray analysis of erythroid cell lines overexpressing human and mouse MFSD2B study showed sphingosine 1-phosphate (S1P) transport activity. The properties of S1P release by MFSD2B were similar to those in erythrocytes. Moreover, knockout of MFSD2B in MEDEP-E14 cells decreased S1P export from the cells. These results strongly suggest that MFSD2B is a novel S1P transporter in erythroid cells. | 29563527 |
| 2018-03-24 10:11:00 | S1P secretion by Mfsd2b is critical for red blood cell morphology; data reveal an unexpected physiological role of red blood cells in sphingolipid metabolism in circulation; findings open new avenues for investigating the signalling roles of S1P derived from red blood cells and platelets | 29045386 |
| 2017-09-23 12:51:00 | MFSD2B, CCL20 and or STARD7 and ZNF512 genes may be risk or protect factors in prognosis of ADC; HTR2B, DPP4, and TGFBRAP1 genes may be risk factors in prognosis of SQC. | 27301951 |
| 2010-01-21 00:00:00 | Results identify Mfsd2a (major facilitator superfamily domain-containing protein 2a) and an additional closely related protein Mfsd2b, and suggest that Mfsd2a plays a role in adaptive thermogenesis. | 18694395 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
MFS2B_HUMAN
UniprotKB:
A6NFX1
UniParc:
UPI000047F9C2
EMBL:
BX357394,
AC008073,
AC104665
Ensembl:
ENSG00000205639
KO:
hsa:388931
|
| Nucleutide sequences |
Ensembl_TRS:
ENST00000338315
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000342501
RefSeq:
NP_001333809.1,
XP_016859553.1,
XP_016859556.1,
XP_016859555.1,
XP_016859559.1,
XP_016859554.1,
XP_016859558.1,
XP_016859552.1,
XP_016859557.1
|
| Others |
UniRef100:
UniRef100_A6NFX1
UniRef90:
UniRef90_A6NFX1
UniRef50:
UniRef50_A6NFX1
UniGene:
Hs.407482
CCDS:
CCDS86824.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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