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38879 pbl

38879

pbl

pebble

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition pebble

研究结论

Date Results Publications
2018-06-09 10:06:00 The PDZ domain binding motif found in the most C-terminal region of the Sema-1a ICD is necessary for interaction with Vari, but not Cher, indicative of distinct binding modalities. Pbl/Sema-1a-mediated repulsive guidance is potentiated by both vari and cher Genetic analyses further suggest that scaffolding functions of Vari and Cher play an important role in Pbl-mediated Sema-1a reverse signaling. 28894005
2017-12-09 11:30:00 RhoGEF2, Pbl, RhoGEF3, and Tum exhibit discrete localization patterns and are required for cell wound repair. 28923977
2014-02-15 12:06:00 Both Pbl and ECT2 repress Wg/Wnt target gene expression in cultured Drosophila and human cells. 24198276
2013-07-27 11:49:00 Reduced cytokinesis may be responsible for the left-right defects in the hindgut of embryos homozygous for pbl. 23041176
2013-05-25 11:00:00 early Drosophila embryogenesis is primed to form furrows at either overlapping astral microtubules or the central spindle; the shift to the latter is driven by a corresponding shift from RhoGEF2 to Pebble in controlling furrow formation. 23022066

名称对应

Type IDs
Synonymous 0083/20, 0293/09, 0542/03, CG8114, Dmel\CG8114, ECT2, Ect-2, GEF, PBL, Pbl, Pbl/Ect2, anon-WO0172774.22, anon-WO0172774.25, l(3)09645
Gene
UniProtKB-ID: D2NUE8_DROME, Q9U7D8_DROME, A8JNN0_DROME, Q8IQ95_DROME, Q8IQ96_DROME, Q8IQ97_DROME
UniprotKB: D2NUE8, Q9U7D8, A8JNN0, Q8IQ95, Q8IQ96, Q8IQ97
UniParc: UPI0000007379, UPI00000845BD, UPI00015D9A53, UPI00000845BE, UPI00000845BF, UPI0001C12940
EMBL: AF136492, AE014296, BT150408, BT120091
EnsemblGenome: FBgn0003041
KO: dme:Dmel_CG8114
Nucleutide sequences
EMBL-CDS: ADB04948.1, AFH04332.1, AAD52845.1, AAF50508.2, AHA95712.1, ABW08489.1, AAN12030.1, AAN12029.1, AAN12028.1
Gene_ORFName: CG8114, Dmel_CG8114, Dmel_CG8114, CG8114, CG8114, Dmel_CG8114, CG8114, Dmel_CG8114, CG8114, Dmel_CG8114, Dmel_CG8114, CG8114
EnsemblGenome_TRS: FBtr0306647, FBtr0076771, FBtr0112817, FBtr0076774, FBtr0076773, FBtr0076772
Protein sequencees
EnsemblGenome_PRO: FBpp0297602, FBpp0076486, FBpp0111729, FBpp0076489, FBpp0076488, FBpp0076487
RefSeq: NP_729306.1, NP_523965.2, NP_001246661.1, NP_729308.1, NP_001097540.1, NP_729307.1
Others
UniRef100: UniRef100_Q8IQ97, UniRef100_Q9U7D8, UniRef100_Q8IQ96, UniRef100_D2NUE8, UniRef100_A8JNN0, UniRef100_Q8IQ95
UniRef90: UniRef90_Q8IQ97, UniRef90_Q9U7D8
UniRef50: UniRef50_Q9U7D8, UniRef50_Q8IQ97
UniGene: Dm.2712

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