| Type | Description |
|---|---|
| Definition | filaggrin family member 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-13 18:51:00 | Filaggrin and filaggrin 2 processing are linked together through skin aspartic acid protease activation. | 32437351 |
| 2020-07-27 13:43:00 | Data suggest that innate immunity of skin involves FLG2, which is expressed in high abundance in upper epidermis/eccrine sweat glands; C-terminal peptide fragments of FLG2 exhibit antimicrobial functions against replication of Pseudomonas aeruginosa and E. coli. | 26371476 |
| 2020-06-13 12:25:00 | In a stop codon variant (rs12568784 G/T) in the FLG2 gene. | 31079484 |
| 2020-05-09 11:12:00 | Study data demonstrate that FLG2 N-terminal part, including A-type repeats, is incorporated in cornified envelopes. Thus, FLG2 and FLG have overlapping roles in the homeostasis of the epidermal barrier. | 30528829 |
| 2019-06-29 11:04:00 | results demonstrate that GATA3 is involved in the regulation of filaggrin and filaggrin-2 expression during inflammatory conditions in the skin. | 28928464 |
| Type | IDs |
|---|---|
| Synonymous | IFPS, PSS6 |
| Gene |
UniProtKB-ID:
FILA2_HUMAN
UniprotKB:
Q5D862
UniParc:
UPI00004E1DE5
EMBL:
DQ118293,
AY827490,
AL356504
Ensembl:
ENSG00000143520
KO:
hsa:388698
|
| Nucleutide sequences |
EMBL-CDS:
AAX12417.1,
AAZ99029.1
Ensembl_TRS:
ENST00000388718
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000373370
RefSeq:
XP_011507833.1,
NP_001014364.1
|
| Others |
UniRef100:
UniRef100_Q5D862
UniRef90:
UniRef90_Q5D862
UniRef50:
UniRef50_Q5D862
UniGene:
Hs.156124
CCDS:
CCDS30861.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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