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388697 HRNR

388697

HRNR

hornerin

protein-coding

Homo sapiens

基因描述

Type Description
Definition hornerin

研究结论

Date Results Publications
2019-02-23 11:07:00 high order repeat formation conserved in apes 30256937
2018-10-27 10:45:00 HRNR promotes tumor progression and is correlated with a poor hepatocellular carcinoma (HCC)prognosis. HRNR may contribute to HCC progression via the regulation of the AKT pathway. 30103712
2018-01-13 12:51:00 These results indicate that hornerin is highly expressed in pancreatic tumor endothelium and alters tumor vessel parameters through a VEGF-independent mechanism. Angiogenesis is essential for solid tumor progression. 28916756
2017-08-12 11:40:00 HRNR gene function is a target of FLG adaptive sweep, and the functional FLG variants that involve susceptibility to atopic dermatitis, seem to hitchhike the selective sweep on HRNR. 27678121
2017-07-22 10:57:00 HRNR deimination improves its cross-linking by TGases and its proteolytic processing by calpain-1. 27742573

名称对应

Type IDs
Synonymous FLG3, S100A16, S100a18
Gene
UniProtKB-ID: HORN_HUMAN
UniprotKB: Q86YZ3
UniParc: UPI00001D7CAD
EMBL: AL589986, AB104446, BR000036, AY396741
Ensembl: ENSG00000197915
KO: hsa:388697
Nucleutide sequences
EMBL-CDS: BAC57496.1, FAA00004.1, AAR91619.1
Ensembl_TRS: ENST00000368801
Protein sequencees
Ensembl_PRO: ENSP00000357791
RefSeq: NP_001009931.1
Others
UniRef100: UniRef100_Q86YZ3
UniRef90: UniRef90_Q86YZ3
UniRef50: UniRef50_Q86YZ3
UniGene: Hs.490162
CCDS: CCDS30859.1

全选

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研究热度

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