| Type | Description |
|---|---|
| Definition | liquid facets |
| Date | Results | Publications |
|---|---|---|
| 2017-12-23 11:50:00 | DSL ligands activate Notch by inducing proteolytic cleavage of the receptor ectodomain that requires ligand to be endocytosed in signal-sending cells by the adaptor protein Epsin; results suggest that once ligand binds receptor, activation depends on a competition between Epsin-mediated ligand endocytosis, which induces cleavage, and transendocytosis of the ligand by the receptor, which aborts the incipient signal. | 29195077 |
| 2012-04-14 10:48:00 | All of the data were consistent with a model where Epsin's essential function is to link ubiquitinated Notch ligands to Clathrin-coated vesicles through other Clathrin adapter proteins. | 22265678 |
| 2010-01-21 00:00:00 | both Dmib and Epsin are required in these cells for some of the endocytic events that internalize DSL ligands | 15930117 |
| 2010-01-21 00:00:00 | Lqf is essential to the receptor-mediated endocytosis of larval serum proteins (LSPs) in the larval fat body cells of Drosophila. | 19305132 |
| 2010-01-21 00:00:00 | Lqf plays distinct roles in two ubiquitin pathways to regulate structural and functional plasticity of the synapse | 18796008 |
| Type | IDs |
|---|---|
| Synonymous | 0110/27, CG8532, Dmel\CG8532, E(faf)bE25, Epsin, LqF, Lqf, anon-WO0118547.239, dEpsin, epsin, l(3)S011027 |
| Gene |
UniProtKB-ID:
Q7KU90_DROME,
M9PEM7_DROME,
Q7KU93_DROME,
Q9VS85_DROME,
M9PEF2_DROME,
M9PBU6_DROME,
A8JNM3_DROME
UniprotKB:
Q7KU90,
M9PEM7,
Q7KU93,
Q9VS85,
M9PEF2,
M9PBU6,
A8JNM3
UniParc:
UPI00001E191D,
UPI000034DECC,
UPI000293EF68,
UPI0002942BA0,
UPI00001E191C,
UPI0000078ABB,
UPI00001E191E
EMBL:
BT133163,
AE014296
EnsemblGenome:
FBgn0028582
KO:
dme:Dmel_CG8532
|
| Nucleutide sequences |
EMBL-CDS:
AAN12041.1,
AAF50542.2,
AGB94220.1,
AGB94225.1,
AAN12042.2,
AGB94221.1,
AGB94224.1,
AEZ02856.1,
AAF50543.3,
AAS65058.1,
AGB94223.1,
AGB94222.1,
ABW08482.1
Gene_ORFName:
Dmel_CG8532,
CG8532,
CG8532,
Dmel_CG8532,
Dmel_CG8532,
CG8532,
Dmel_CG8532,
CG8532,
CG8532,
Dmel_CG8532,
CG8532,
Dmel_CG8532,
Dmel_CG8532,
CG8532
EnsemblGenome_TRS:
FBtr0076794,
FBtr0076796,
FBtr0331838,
FBtr0331833,
FBtr0331837,
FBtr0331834,
FBtr0076797,
FBtr0076795,
FBtr0076798,
FBtr0331836,
FBtr0331835,
FBtr0112941
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0076508,
FBpp0076510,
FBpp0304222,
FBpp0304217,
FBpp0304221,
FBpp0089150,
FBpp0304218,
FBpp0076509,
FBpp0089151,
FBpp0304220,
FBpp0304219,
FBpp0111854
RefSeq:
NP_001261526.1,
NP_001261527.1,
NP_001261528.1,
NP_523962.2,
NP_729267.1,
NP_001261525.1,
NP_729268.2,
NP_729266.2,
NP_996013.1,
NP_001097529.1,
NP_001261530.1,
NP_001261529.1
|
| Others |
UniRef100:
UniRef100_M9PBU6,
UniRef100_A8JNM3,
UniRef100_M9PEF2,
UniRef100_Q9VS85
UniRef90:
UniRef90_A8JNM3,
UniRef90_M9PEF2,
UniRef90_Q9VS85
UniRef50:
UniRef50_A8JNM3,
UniRef50_M9PEF2,
UniRef50_Q9VS85
UniGene:
Dm.2223
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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