| Type | Description |
|---|---|
| Definition | ras homolog family member B |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:12:00 | CSN5 inhibition triggers inflammatory signaling and Rho/ROCK-dependent loss of endothelial integrity. | 31148579 |
| 2020-05-16 13:03:00 | It findings identify a novel regulatory mechanism for RhoB localization and stability by Arf6 and establish the strict requirement of Arf6 for RhoB-specific subcellular targeting to endosomes and biological functions. | 31591185 |
| 2020-04-25 11:27:00 | We found that RhoB, but not RhoA or RhoC, is in resting endothelium a negative regulator of permeability. Loss of RhoB accounted for an accumulation of VE-cadherin at cell-cell contacts. Thrombin-induced loss of endothelial integrity is mediated primarily by RhoA and RhoB. | 28949796 |
| 2019-12-21 12:14:00 | Cytoplasmic p27(Kip1) promotes tumorigenesis by suppressing RhoB activity in non-small cell lung carcinoma cells. | 30206932 |
| 2019-11-23 10:38:00 | This data demonstrated that miR-19a promoted the invasion and EMT through targeting RhoB. It is suggested that miR-19a/RhoB axis may show a new way for the treatment of bladder cancer. | 31128038 |
| Type | IDs |
|---|---|
| Synonymous | ARH6, ARHB, MST081, MSTP081, RHOH6 |
| Gene |
UniProtKB-ID:
RHOB_HUMAN
UniprotKB:
P62745
UniParc:
UPI0000021989
EMBL:
M12174,
BT019547,
AK124398,
AF498971,
BT019546,
BK001671,
CH471053,
BK001232,
X06820,
AK312487,
AC023137,
BC066954,
CR542272
Ensembl:
ENSG00000143878
KO:
hsa:388
|
| Nucleutide sequences |
EMBL-CDS:
AAM21118.1,
AAA36565.1,
AAV38353.1,
DAA01912.1,
DAA01138.1,
AAV38354.1,
EAX00820.1,
AAH66954.1,
BAG35389.1,
BAG54035.1,
CAG47068.1,
AAY24345.1,
EAX00819.1,
CAA29968.1
Ensembl_TRS:
ENST00000272233
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000272233
RefSeq:
NP_004031.1
|
| Others |
UniRef100:
UniRef100_P62745
UniRef90:
UniRef90_P62745
UniRef50:
UniRef50_P62745
UniGene:
Hs.502876
CCDS:
CCDS1699.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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