| Type | Description |
|---|---|
| Definition | thymocyte selection associated |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 11:25:00 | THEMIS-SHP1 Recruitment by 4-1BB Tunes LCK-Mediated Priming of Chimeric Antigen Receptor-Redirected T Cells | 32004441 |
| 2017-07-22 12:25:00 | we have demonstrated mutually exclusive use of exon 1 and 2 amongst 16 novel THEMIS isoforms. We also show inverse correlation between THEMIS expression in human CD4+ T-cells and dosage of the multiple sclerosis risk allele at rs13204742, driven by reduced expression of exon 1- containing isoforms | 27438997 |
| 2017-06-24 10:54:00 | we found that THEMIS directly regulated the catalytic activity of the tyrosine phosphatase SHP-1. | 28250424 |
| 2015-03-28 11:51:00 | the THEMIS:SHP complex dampens early TCR signalling by a previously unknown molecular mechanism that favours T-cell survival. | 25535246 |
| 2014-10-11 11:03:00 | THEMIS showed higher mRNA expression in active celiac disease compared with treated patients and controls. | 23820479 |
| Type | IDs |
|---|---|
| Synonymous | C6orf190, C6orf207, GASP, SPOT, TSEPA |
| Gene |
UniProtKB-ID:
THMS1_HUMAN
UniprotKB:
Q8N1K5
UniParc:
UPI000022CCBA,
UPI00001C1E44,
UPI0001B3CB2F,
UPI000022CCBB
EMBL:
BX640890,
AL035470,
CH471051,
AK094863,
AK292046,
AK124031,
AL365224,
AK097903,
BC130516,
AK128377,
AL356432
Ensembl:
ENSG00000172673,
ENSG00000275122
KO:
hsa:387357
|
| Nucleutide sequences |
EMBL-CDS:
BAG54669.1,
BAG53994.1,
BAG52943.1,
BAF84735.1,
CAE45941.1,
AAI30517.1,
EAW48092.1,
BAC05194.1
Ensembl_TRS:
ENST00000368248,
ENST00000630369,
ENST00000537166,
ENST00000368250,
ENST00000613862,
ENST00000610842,
ENST00000614155
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000487358,
ENSP00000480630,
ENSP00000357233,
ENSP00000484170,
ENSP00000480967,
ENSP00000357231,
ENSP00000439863
RefSeq:
NP_001010923.1,
NP_001305460.1,
XP_011534118.1,
XP_011534116.1,
XP_016866338.1,
XP_024302202.1,
NP_001158157.1,
NP_001158159.1,
XP_024302201.1,
XP_016866337.1
|
| Others |
UniRef100:
UniRef100_Q8N1K5
UniRef90:
UniRef90_Q8N1K5
UniRef50:
UniRef50_Q8BGW0
UniGene:
Hs.661756
CCDS:
CCDS55056.1,
CCDS55055.1,
CCDS34534.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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