| Type | Description |
|---|---|
| Definition | hypocretin (orexin) receptor 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-06-24 12:12:00 | Study demonstrated that activation of the OX1 receptor in the ventrolateral periaqueductal gray of mice can initiate an endocannabinoid-CB1 receptor-mediated analgesia. Activation of the OX2 receptor in the ventrolateral periaqueductal gray was also antinociceptive but this antinociceptive effect is CB1 receptor-independent. | 26907809 |
| 2017-01-28 10:07:00 | Elevation levels of OX1R and OX2R following experimental autoimmune encephalomyelitis induction suggest that alteration in orexinergic system may involve in pathogenesis of multiple sclerosis. | 26996108 |
| 2016-04-16 10:11:00 | In an heart failure model, HCRTR2-deficient mice exhibited poorer cardiac function, worse treadmill exercise capacity, and greater myocardial scarring | 26653627 |
| 2015-06-20 12:42:00 | orexin activation of OX2R in the brain centrally enhances bone formation by lowing circulating leptin level. | 24794976 |
| 2014-10-11 12:25:00 | Knocking down the Orx2 receptors in the basolateral amygdala increased anxious behavior as measured by reduced social preference and reduced time spent in the center of an open field. | 24485472 |
| Type | IDs |
|---|---|
| Synonymous | OX2R, OX2aR, OX2bR, OXR2, mOX2aR, mOX2bR, mOXR2 |
| Gene |
UniProtKB-ID:
OX2R_MOUSE
UniprotKB:
P58308
UniParc:
UPI00001F7AE1,
UPI00000EBA78
EMBL:
AY339386,
AK048781,
AY339387,
AY339388,
AY336085,
AY339383,
AF394597,
AY339384,
AK038551,
AY339390,
AY339389,
AY339385,
AY336084
Ensembl:
ENSMUSG00000032360
KO:
mmu:387285
|
| Nucleutide sequences |
EMBL-CDS:
AAR11293.1,
AAR01327.1,
AAR01328.1,
AAR11294.1,
AAK71327.1,
BAC30039.1,
BAC33457.1
Ensembl_TRS:
ENSMUST00000184757,
ENSMUST00000063140
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000139377,
ENSMUSP00000058230
RefSeq:
NP_945200.1,
NP_001351480.1
|
| Others |
UniRef100:
UniRef100_P58308
UniRef90:
UniRef90_O43614
UniRef50:
UniRef50_O43614
UniGene:
Mm.335300
CCDS:
CCDS23350.1,
CCDS90628.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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