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387189 Mir194-1

387189

Mir194-1

microRNA 194-1

ncRNA

Mus musculus

基因描述

Type Description
Definition microRNA 194-1

研究结论

Date Results Publications
2021-03-06 13:31:00 MicroRNA Binding Site Polymorphisms of the Long-Chain MALAT1 are Associated with Risk and Prognosis of Colorectal Cancer in Chinese Han Population. 32349546
2021-02-06 13:49:00 Downregulation of circulating miR 802-5p and miR 194-5p and upregulation of brain MEF2C along breast cancer brain metastasization. 31930767
2020-02-15 12:28:00 In liver fibrosis MiR-194 expression was notably lacking in activated hepatic stellate cells (HSCs) from both humans and mice. Overexpression of miR-194 suppressed HSCs cell proliferation by cell cycle arrest in G0/G1 phase. AKT2 was predicted to be a target of miR-194. Results suggest that miR-194 plays a protective role in liver cirrhosis by inhibiting the activation and proliferation of HSCs via AKT2 suppression. 31496625
2020-01-04 11:49:00 Overexpression of miR-194 decreased Hnf1beta mRNA and protein level in mouse metanephric mesenchyme cells. In addition, miR-194-decreased cell proliferation and miR-194-promoted cell apoptosis and migration were reversed by overexpression of Hnf1beta coding region. 31144266
2019-01-19 12:15:00 Exosomes from obese mice impaired myocyte mitochondrial activity, but blocking with miR-194 sponge attenuated the exosomal miR-194-induced reduction of ATP production (p<0.05), basal oxygen consumption (p<0.01) and mitochondrial complex I activity (p<0.001). In vivo mouse study, high fat diet damaged cardiac function, normal structure and mitochondrial activity, whereas miR-194 sponge improved the cardiac status. 30170731

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Type IDs
Synonymous Mirn194, Mirn194-1, miR-194, mir-194-1