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387146 Mir127

387146

Mir127

microRNA 127

ncRNA

Mus musculus

基因描述

Type Description
Definition microRNA 127

研究结论

Date Results Publications
2021-02-27 13:49:00 MicroRNA-127-3p regulates myoblast proliferation by targeting Sept7. 32382971
2020-08-01 10:47:00 tight regulation of miR-127-3p is crucial to preserve the self-renewing stem cell pool and homeostasis of the hematopoietic system 30792210
2020-06-20 11:39:00 TUG1 was downregulated in TNF-alpha-treated primary mouse interstitial cells of Cajal (ICC). TUG1 overexpression protected ICC from TNF-alpha-induced apoptosis and pro-inflammatory cytokines expression. MiR-127 was negatively regulated by TUG1 and implicated in the action of TUG1 in ICC. Mechanistically, TUG1 inhibited TNF-alpha-induced activation of NF-kappaB and Notch pathways in ICC by down-regulating miR-127. 30657572
2018-12-22 12:01:00 Overexpression of miR-127-3p almost has no effects on differentiation of C2C12cell lines. However, miR-127-3p significantly inhibited the cell proliferation of C2C12cells. KMT5a was identified as a target gene that was down-regulated in both mRNA and protein level when miR-127-3p mimics were introduced. 29932923
2018-05-19 11:37:00 upregulation of miR127 expression may contribute to the development of ventilatorinduced lung injury. 28765901

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Type IDs
Synonymous Mirn127, mir-127, mmu-mir-127