| Type | Description |
|---|---|
| Definition | centromere protein W |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 10:20:00 | The novel CUG2 oncogene promotes cellular transformation and stemness, mediated by nuclear NPM1 protein and TGF-beta signaling. | 31113615 |
| 2019-12-14 11:19:00 | CUG2 enhances expression of YAP1 protein. Akt and MAPK kinases are involved in the increase of YAP1 protein expression under overexpression of CUG2. | 30771899 |
| 2019-08-31 13:24:00 | Study provide new evidence to suggest that CUG2 overexpression contributes to tumor formation through NEK2/beta-catenin signaling by enhancing the phosphorylation of betacatenin at Ser33/Ser37 by activating NEK2, thus stabilizing betacatenin. | 30968157 |
| 2019-04-06 10:03:00 | CENP-W showed a higher affinity toward the beta-TrCP1 b isoform. | 30267325 |
| 2018-12-29 10:03:00 | we suggest that signaling induces malignant tumor features such as EMT and sphere formation in CUG2overexpressing cancer cells. | 30226605 |
| Type | IDs |
|---|---|
| Synonymous | C6orf173, CENP-W, CUG2 |
| Gene |
UniProtKB-ID:
CENPW_HUMAN,
A0A0A0MRK5_HUMAN
UniprotKB:
Q5EE01,
A0A0A0MRK5
UniParc:
UPI000013FCDF,
UPI000020E1D8,
UPI000059D927
EMBL:
BC017928,
BC039556,
BC062798,
AC020559,
BC046178,
AY902475,
CH471051
Ensembl:
ENSG00000203760
KO:
hsa:387103
|
| Nucleutide sequences |
EMBL-CDS:
AAH62798.1,
AAH17928.1,
EAW48121.1,
EAW48122.1,
AAW82474.1,
AAH46178.1,
EAW48123.1,
AAH39556.1
Ensembl_TRS:
ENST00000368325,
ENST00000368328,
ENST00000368326
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000357311,
ENSP00000357308,
ENSP00000357309
RefSeq:
NP_001012525.1,
NP_001273454.1,
NP_001273453.1,
XP_016866334.1
|
| Others |
UniRef100:
UniRef100_Q5EE01,
UniRef100_A0A0A0MRK5
UniRef90:
UniRef90_Q5EE01,
UniRef90_A0A0A0MRK5
UniRef50:
UniRef50_Q5EE01,
UniRef50_A0A0A0MRK5
UniGene:
Hs.486401
CCDS:
CCDS34529.1,
CCDS69196.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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