| Type | Description |
|---|---|
| Definition | small ubiquitin like modifier 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:29:00 | Small ubiquitin-related modifier (SUMO) 3 and SUMO4 gene polymorphisms in Parkinson's disease. | 32237992 |
| 2019-01-12 12:09:00 | Donor SUMO4 rs237025 genetic variant was associated with higher tacrolimus C/D ratios in the early period after liver transplantation, which might be related to the down-regulation of CYP3A5 enzyme through the NF-kB signalling pathway. | 28941036 |
| 2017-10-14 10:50:00 | meta-analysis demonstrated that the G allele of the SUMO4 M55V polymorphism could be a susceptible risk locus to type 2 diabetes mellitus, mainly in the Chinese population, while the association in other ethnic population needs to be further validated | 28494838 |
| 2017-09-23 13:23:00 | Both donor and recipient SUMO4 rs237025 polymorphisms contribute to the development of new-onset diabetes mellitus after liver transplantation. | 28689037 |
| 2017-09-23 11:19:00 | Results show that SUMO-4 is expressed in normal placental development. SUMO-4 expression was increased in pre-eclamptic placentas and in models of oxidative stress and hypoxic injury suggesting that SUMO-4 hyper-SUMOylation may be a potential post-translational mechanism in the stressed pre-eclamptic placenta. | 28545138 |
| Type | IDs |
|---|---|
| Synonymous | IDDM5, SMT3H4, SUMO-4, dJ281H8.4 |
| Gene |
UniProtKB-ID:
SUMO4_HUMAN
UniprotKB:
Q6EEV6
UniParc:
UPI00005D3C1C
EMBL:
AB205057,
CH471051,
BC130305,
AL031133,
AY340238
Ensembl:
ENSG00000177688
KO:
hsa:387082
|
| Nucleutide sequences |
EMBL-CDS:
BAH05006.1,
AAR04484.1,
AAI30306.1,
EAW47808.1
Ensembl_TRS:
ENST00000326669
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000318635
RefSeq:
NP_001002255.1
|
| Others |
UniRef100:
UniRef100_Q6EEV6
UniRef90:
UniRef90_Q6EEV6
UniRef50:
UniRef50_Q6EEV6
UniGene:
Hs.657168
CCDS:
CCDS34549.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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