| Type | Description |
|---|---|
| Definition | platelet-derived growth factor receptor, alpha polypeptide |
| Date | Results | Publications |
|---|---|---|
| 2018-02-10 10:34:00 | Timelapse analysis of individual cardiomyocyte trajectories reveals misdirected cells in zebrafish pdgfra mutants, suggesting that PDGF signaling steers cardiomyocytes toward the midline during cardiac fusion. Intriguingly, the ligand pdgfaa is expressed in the endoderm medial to the pdgfra-expressing myocardial precursors. | 28098558 |
| 2017-09-09 11:40:00 | Pdgf/Pdgfr signalling guides neural crest contribution to the haematopoietic stem cell specification niche. | 28394883 |
| 2013-09-28 10:41:00 | Untreated pdgfra mutants have cleft palate due to defective neural crest cell migration, whereas pdgfra heterozygotes develop normally. | 23861062 |
| 2013-01-10 05:46:00 | The conserved regulatory interactions of mirn140 and pdgfra define an ancient mechanism of palatogenesis, and they provide candidate genes for cleft palate. | 18264099 |
| 2013-01-10 05:46:00 | Protean differentiation and proliferation pathways are commonly regulated by PDGFRa, PDGFRb and PDGFRa/b while each receptor is also responsible for regulating unique signaling pathways. Some signaling is solely modulated through heterodimeric PDGFRa/b. | 19030102 |
| Type | IDs |
|---|---|
| Synonymous | etID309717.20, pdgfr-a, wu:fc27f02, wu:fv91b12 |
| Gene |
UniProtKB-ID:
PGFRA_DANRE
UniprotKB:
Q9DE49
UniParc:
UPI00000FD2E1
EMBL:
AF200951
KO:
dre:386856
|
| Nucleutide sequences |
EMBL-CDS:
AAG43479.1
|
| Protein sequencees |
RefSeq:
NP_571534.1
|
| Others |
UniRef100:
UniRef100_Q9DE49
UniRef90:
UniRef90_Q9DE49
UniRef50:
UniRef50_Q9DE49
UniGene:
Dr.75077
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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