| Type | Description |
|---|---|
| Definition | APC regulator of WNT signaling pathway |
| Date | Results | Publications |
|---|---|---|
| 2015-05-21 09:39:00 | APC controls the production of RA in the gut by regulating the expression of the retinol dehydrogenase, rdh1l | 15967793 |
| 2014-09-13 10:05:00 | Apc mutations activate mechanistic target of rapamycin complex 1 in mice and zebrafish | 24092877 |
| 2012-06-23 10:47:00 | Mutations in APC, a negative regulator of the Wnt/ss-catenin pathway, can cause cancer as well as profound developmental defects. | 22136118 |
| 2010-10-23 10:13:00 | Study shows that homozygous loss of APC causes robust upregulation of the components of the demethylase and that this impairs the proper differentiation of intestinal cells. | 20850014 |
| 2010-09-27 12:41:00 | Data show a loss of adenomatous polyposis coli (apc) results in an expanded ciliary marginal zone in the zebrafish eye. | 20549742 |
| Type | IDs |
|---|---|
| Synonymous | cb965, im:7150932, im:7152872 |
| Gene |
UniProtKB-ID:
A0A0R4IWH7_DANRE,
F8W4Z3_DANRE
UniprotKB:
A0A0R4IWH7,
F8W4Z3
UniParc:
UPI0000F1EE41,
UPI00021512A6
EMBL:
CU915637,
CU861476
Ensembl:
ENSDARG00000058868
KO:
dre:386762
|
| Nucleutide sequences |
Ensembl_TRS:
ENSDART00000158897,
ENSDART00000149956
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000139275,
ENSDARP00000123835
RefSeq:
NP_001137312.1,
XP_005155580.1,
XP_017213427.1
|
| Others |
UniRef100:
UniRef100_F8W4Z3,
UniRef100_A0A0R4IWH7
UniRef90:
UniRef90_F8W4Z3
UniRef50:
UniRef50_P70039
UniGene:
Dr.76198,
Dr.160758
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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