| Type | Description |
|---|---|
| Definition | NSFL1 (p97) cofactor (p47) |
| Date | Results | Publications |
|---|---|---|
| 2018-01-27 11:14:00 | our data identify EBP50 as a previously unidentified regulator of Nox1 and support that it promotes Nox1 activity by binding p47(phox) This interaction is pivotal for agonist-induced smooth muscle hypertrophy, and vasoconstriction and has implications for physiological and pathophysiological processes. | 27540115 |
| 2013-11-02 10:23:00 | Data suggest that NADPH oxidase-derived cytosolic superoxide is increased in islets upon oleate exposure and leads to beta cell dysfunction; whole-body NADPH oxidase inhibition (via p47 knockout) decreases superoxide and restores islet function. | 23429921 |
| 2010-01-21 00:00:00 | genetic ablation of components of NADPH oxidase enhances susceptibility to the proinflammatory effects of CS leading to airspace enlargement and alveolar damage. | 18403597 |
| 2010-01-21 00:00:00 | that p47 ubiquitin regulatory X domain domains may act as general p97/valosin containing protein/CDC48 binding modules and that adaptor binding for N-ethylmaleimide sensitive factor and p97 might involve different binding sites | 14988733 |
| Type | IDs |
|---|---|
| Synonymous | Munc-18c, Stxbp3a, p47 |
| Gene |
UniProtKB-ID:
NSF1C_MOUSE,
Q3UVN5_MOUSE
UniprotKB:
Q9CZ44,
Q3UVN5
UniParc:
UPI000018FE32,
UPI0000232DED,
UPI000002762D
EMBL:
AK137088,
AL928719,
AK039136,
AK013024,
BC050936
Ensembl:
ENSMUSG00000027455
KO:
mmu:386649
|
| Nucleutide sequences |
EMBL-CDS:
BAB28604.1,
BAC30250.1,
AAH50936.1,
BAE23234.1
Ensembl_TRS:
ENSMUST00000028949,
ENSMUST00000089140
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000086542,
ENSMUSP00000028949
RefSeq:
NP_938085.1,
NP_001278003.1
|
| Others |
UniRef100:
UniRef100_Q9CZ44,
UniRef100_Q3UVN5
UniRef90:
UniRef90_O35987
UniRef50:
UniRef50_O35987
UniGene:
Mm.419479
CCDS:
CCDS71160.1,
CCDS16868.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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